MUC-17

MUC-17 Molekülinformation

Englischer Name	Mucin-17	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	3	Target-Alias	Small intestinal mucin-3，MUC-3
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Englischer Name	Mucin-17
Target-Alias	Small intestinal mucin-3，MUC-3
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	3
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

MUC-17 Produktliste

Attribut
Protein (2)
Produktbibliothek
Online (2)
Spezies
Human (2)
Etikett
His Tag (1)His Tag & Avi Tag (1)
Marker
Unconjugated (1)Biotin-labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
MU7-H52H3	Human	HEK293	Human MUC-17 Protein, His Tag				In den Warenkorb legen
MU7-H82E3	Human	HEK293	Biotinylated Human MUC-17 Protein, His,Avitag™				In den Warenkorb legen

Gesamtmenge2

MUC-17 Molekülhintergrund

Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.

MUC-17 Molekülalias

Mucin-17,MUC-17,MUC17,MUC-3,MUC3

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
ZGGS-34	ZGGS34; ZGGS-34	Phase 2 Clinical	Suzhou Zelgen Biopharmaceuticals Co Ltd	Solid tumours	Details
HDM-2012	HDM-2012	Phase 1 Clinical	Hangzhou Zhongmei Huadong Pharmaceutical Co Ltd	Solid tumours	Details
SSS-59	SSS59; SSS-59	Phase 1 Clinical	Shenyang Sunshine Pharmaceutical Co Ltd	Neoplasms	Details