LIV-1

LIV-1 Molekülinformation

Englischer Name	Zinc transporter ZIP6	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	2	Target-Alias	LIV-1，LIV1，LIV-1 Protein， Estrogen Regulated，Solute Carrier Family 39 (Metal Ion Transporter)， Member 6，Zrt- and Irt-like protein 6，SLC39A6，Estrogen-regulated protein LIV-1，ZIP-6，Zinc transporter ZIP6，Solute Carrier Family 39 (Zinc Transporter)， Member 6，Solute carrier family 39 member 6
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Englischer Name	Zinc transporter ZIP6
Target-Alias	LIV-1，LIV1，LIV-1 Protein， Estrogen Regulated，Solute Carrier Family 39 (Metal Ion Transporter)， Member 6，Zrt- and Irt-like protein 6，SLC39A6，Estrogen-regulated protein LIV-1，ZIP-6，Zinc transporter ZIP6，Solute Carrier Family 39 (Zinc Transporter)， Member 6，Solute carrier family 39 member 6
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	2
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

LIV-1 Produktliste

Attribut
Protein (14)
Produktbibliothek
Online (14)
Spezies
Human (7)Cynomolgus (3)Rat (1)Mouse (2)Rhesus macaque (1)
Etikett
Fc Tag (4)His Tag (6)His Tag & Avi Tag (2)Fc Tag & Avi Tag (1)- (1)
Marker
Unconjugated (11)Biotin-labeled (3)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT LV1-H5223	Human	HEK293	Human LIV-1 / SLC39A6 Protein, His Tag	In den Warenkorb legen
HOT LV1-H82E3	Human	HEK293	Biotinylated Human LIV-1 / SLC39A6 Protein, His,Avitag™	In den Warenkorb legen
HOT LV1-C52H5	Cynomolgus	HEK293	Cynomolgus LIV-1 / SLC39A6 Protein, His Tag	In den Warenkorb legen
HOT LV1-R52H9	Rat	HEK293	Rat LIV-1 / SLC39A6 Protein, His Tag	In den Warenkorb legen
LV1-H5254	Human	HEK293	Human LIV-1 / SLC39A6 Protein, Fc Tag (MALS verified)	In den Warenkorb legen
LV1-H5255	Human	HEK293	Human LIV-1 / SLC39A6 Protein, Fc Tag, low endotoxin	In den Warenkorb legen
LV1-H5257	Human	HEK293	Human LIV-1 / SLC39A6 (229-325) Protein, Fc Tag (MALS verified)	In den Warenkorb legen
LV1-H52P3	Human	HEK293	Human LIV-1 Full Length Protein (VLP)	In den Warenkorb legen
LV1-H82F5	Human	HEK293	Biotinylated Human LIV-1 / SLC39A6 Protein, Fc,Avitag™ (MALS verified)	In den Warenkorb legen
LV1-M5253	Mouse	HEK293	Mouse LIV-1 / SLC39A6 Protein, Fc Tag (MALS verified)	In den Warenkorb legen

Gesamtmenge14

LIV-1 Molekülhintergrund

LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines.

LIV-1 Molekülalias

SLC39A6,LIV-1,ZIP6,Zinc transporter ZIP6,ZIP-6

Antikörperprojekt-Handelsplattform

Projektname	Projektphase	Molekültyp	Molekülquelle	Krankheitsgebiet	Indikationen
LIV-1 mAb - 01	PCC	Monoclonal	Humanized Mouse	Solid Tumor	Colorectal cancer,Breast cancer

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Ladiratuzumab vedotin	SGN-LIV1A; MK-6440; MK6440	Phase 2 Clinical	Merck Sharp & Dohme Corp, Seagen Inc	Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Esophageal Squamous Cell Carcinoma; Gastroesophageal Junction Neoplasms; Melanoma; Metastatic breast cancer; Prostatic Neoplasms; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Triple Negative Breast Neoplasms	Details
Laventatug	BRY-812	Phase 2 Clinical	Zhejiang BioRay Biopharmaceuticals Co Ltd	Neoplasms; Solid tumours	Details

Produktrezensionen

J***g2022-04-13
1Menschen mögen
Human LIV-1 / SLC39A6 Protein, His Tag
When I was searching for this protein, there were not many options until I found ACRO. Very happy about various species as well as tag choices. ELISA results are reproducible and consistent. The delivery was fast whereas others may take longer. The product information is clear and comprehensive, which is very important for the research.