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Laminin 211

Laminin 211 Produktliste

  • Attribut

    Protein (1)

  • Produktbibliothek

    Online (1)

  • Spezies

    Human (1)

  • Etikett

    - (1)

  • Marker

    Unconjugated (1)

ProduktnummerSpeziesExpressionssystemProduktbeschreibungProteinstrukturReinheitEigenschaftenVorbestellen/Bestellen
HOT
LA8-H5263
Human
HEK293
Human Laminin 211 Protein, premium grade In den Warenkorb legen
Gesamtmenge1
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Laminin 211 Molekülhintergrund

Laminin-α2 is a critical component of the laminin heterotrimer, which along with laminin-β1 or β2 and laminin-γ1 form the structural glycoproteins laminin-211 and laminin-221 in skeletal muscle. Laminin-211 is the most abundant laminin isoform in the basement membrane of adult skeletal muscle. Laminin-211 and -221 polymerize with each other and interact with nidogen and collagen-IV to form the muscle basal lamina. Laminin-211 and laminin-221 bind to muscle cell surface through the α7β1 integrin and α-dystroglycan of the dystrophin glycoprotein complex via their globular C-terminal domains.

Klinische Arzneimittelinformation

Englischer NameForschungscodeForschungsphaseFirmaIndikationenKlinische Studie
STEMVACEP-101Phase 2 ClinicalEpithanyTriple Negative Breast Neoplasms; Breast Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung
Details
FF-21101-Y-90FF-21101-Y-90; PPMX-T002Phase 1 ClinicalFujifilm Holdings CorpSolid tumours
Details
AMG 305AMG-305; AMG 305Phase 1 ClinicalAmgen IncSolid tumours
Details
BC-3195BC3195; BC-3195Phase 1 ClinicalSolid tumours; Neoplasms; Neoplasm Metastasis
Details
FF-21101YFF-21101YPhase 1 ClinicalPeptidreamSolid tumours
Details
FF-21101InFF-21101InPhase 1 ClinicalPeptidreamSolid tumours
Details
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