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IRAK4

IRAK4 Produktliste

  • Attribut

    Protein (5)

  • Produktbibliothek

    Online (5)

  • Spezies

    Human (2)Canine (1)Mouse (1)Cynomolgus (1)

  • Etikett

    His Tag (4)GST Tag (1)

  • Marker

    Unconjugated (5)

ProduktnummerSpeziesExpressionssystemProduktbeschreibungProteinstrukturReinheitEigenschaftenVorbestellen/Bestellen
AIDD‑Ready
IR4-H5533
Human
InsectCells
Human IRAK4 Protein, GST Tag (active enzyme, HPLC verified)
In den Warenkorb legen
AIDD‑Ready
IR4-H5546
Human
InsectCells
Human IRAK4 Protein, His Tag
In den Warenkorb legen
AIDD‑Ready
IR4-M5544
Mouse
InsectCells
Mouse IRAK4 Protein, His Tag (active enzyme)
In den Warenkorb legen
AIDD‑Ready
IR4-C5545
Canine
InsectCells
Canine IRAK4 Protein, His Tag (active enzyme)
In den Warenkorb legen
AIDD‑Ready
IR4-C5546
Cynomolgus
InsectCells
Cynomolgus IRAK4 Protein, His Tag (active enzyme)
In den Warenkorb legen
Gesamtmenge5
  • 1

IRAK4 Molekülhintergrund

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Klinische Arzneimittelinformation

Englischer NameForschungscodeForschungsphaseFirmaIndikationenKlinische Studie
FiztasovimabNPC-21Phase 2 ClinicalNobelpharma Co LtdCytomegalovirus Infections
Details
TRL-345CMV-345; TRL-345Phase 1 ClinicalTrellis Bioscience LLCCytomegalovirus Infections
Details
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  • Klinische Arzneimittelinformation
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