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IRAK4

IRAK4 Produktliste

  • Attribut

    Protein (5)

  • Produktbibliothek

    Online (5)

  • Spezies

    Human (2)Canine (1)Mouse (1)Cynomolgus (1)

  • Etikett

    His Tag (4)GST Tag (1)

  • Marker

    Unconjugated (5)

IRAK4 Molekülhintergrund

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Klinische Arzneimittelinformation

Englischer NameForschungscodeForschungsphaseFirmaIndikationenKlinische Studie
FiztasovimabNPC-21Phase 2 ClinicalNobelpharma Co LtdCytomegalovirus Infections
Details
TRL-345CMV-345; TRL-345Phase 1 ClinicalTrellis Bioscience LLCCytomegalovirus Infections
Details
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