Integrin alpha 10 beta 1

Integrin alpha 10 beta 1 Molekülinformation

Englischer Name	Integrin alpha10/beta1	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	0	Target-Alias	Integrin alpha-10/Integrin beta-1，Integrin alpha-10/beta-1
Höchste Forschungs- und Entwicklungsphase	Preclinical

Englischer Name	Integrin alpha10/beta1
Target-Alias	Integrin alpha-10/Integrin beta-1，Integrin alpha-10/beta-1
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	0
Höchste Forschungs- und Entwicklungsphase	Preclinical

Integrin alpha 10 beta 1 Produktliste

Attribut
Protein (2)
Produktbibliothek
Online (2)
Spezies
Human (1)Mouse (1)
Etikett
His Tag (2)
Marker
Unconjugated (2)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
IT1-H52Wa	Human	HEK293	Human Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein, His Tag&Tag Free				In den Warenkorb legen
IT1-M52W4	Mouse	HEK293	Mouse Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein, His Tag&Tag Free				In den Warenkorb legen

Gesamtmenge2

Integrin alpha 10 beta 1 Molekülhintergrund

Human integrin alpha(10)I domain as a recombinant protein to reveal its ligand binding specificity. In general, alpha(10)I did recognize collagen types I-VI and laminin-1 in a Mg(2+)-dependent manner, whereas its binding to tenascin was only slightly better than to albumin. Alpha 10 beta 1 is a known collagen-binding I domain integrin, in addition to α1β1, α2β1 and α11β1. GROGER found in the N-terminal domain of collagens I and III, is only weakly recognised by α10β1, an important collagen receptor on chondrocytes, contrasting with the other collagen-binding integrins.