IL-8

IL-8 Molekülinformation

Englischer Name	Interleukin-8	Anzahl der inverkehr gebrachten Arzneimittel	1
Anzahl der klinischen Arzneimittel	6	Target-Alias	IL8/NAP1 form VI，T-cell chemotactic factor，GCP/IL-8 protein III，IL8/NAP1 form II，GCP/IL-8 protein II，(Ala-IL-8)77，Emoctakin，IL8/NAP1 form IV，LYNAP，IL8/NAP1 form III，IL8/NAP1 form V，GCP/IL-8 protein I，Neutrophil-Activating Peptide 1，Interleukin 8，GCP-1，MDNCF，NAP-1，IL8，Beta Endothelial Cell-Derived Neutrophil Activating Peptide，Lung Giant Cell Carcinoma-Derived Chemotactic Protein，Lymphocyte Derived Neutrophil Activating Peptide，Alveolar Macrophage Chemotactic Factor I，Tumor Necrosis Factor-Induced Gene 1，Small Inducible Cytokine Subfamily B， Member 8，Beta-Thromboglobulin-Like Protein，GCP1，LECT，LUCT，NAP1，IL-8，Interleukin-8，AMCF-I，SCYB8，Neutrophil-Activating Protein 1，B-ENAP，3-10C，K60，TSG-1，C-X-C Motif Chemokine Ligand 8，Monocyte-Derived Neutrophil Chemotactic Factor，Monocyte-Derived Neutrophil-Activating Peptide，Granulocyte Chemotactic Protein 1，Chemokine (C-X-C Motif) Ligand 8，(Ser-IL-8)72，Neutrophil-activating factor，MDNCF-c，C-X-C motif chemokine 8，Lymphocyte-derived neutrophil-activating factor，Protein 3-10C，IL-8(1-77)，NAF，GCP/IL-8 protein VI，GCP/IL-8 protein IV，IL8/NAP1 form I，MONAP，MDNCF-b，GCP/IL-8 protein V，CXCL8
Höchste Forschungs- und Entwicklungsphase	Approved

Englischer Name	Interleukin-8
Target-Alias	IL8/NAP1 form VI，T-cell chemotactic factor，GCP/IL-8 protein III，IL8/NAP1 form II，GCP/IL-8 protein II，(Ala-IL-8)77，Emoctakin，IL8/NAP1 form IV，LYNAP，IL8/NAP1 form III，IL8/NAP1 form V，GCP/IL-8 protein I，Neutrophil-Activating Peptide 1，Interleukin 8，GCP-1，MDNCF，NAP-1，IL8，Beta Endothelial Cell-Derived Neutrophil Activating Peptide，Lung Giant Cell Carcinoma-Derived Chemotactic Protein，Lymphocyte Derived Neutrophil Activating Peptide，Alveolar Macrophage Chemotactic Factor I，Tumor Necrosis Factor-Induced Gene 1，Small Inducible Cytokine Subfamily B， Member 8，Beta-Thromboglobulin-Like Protein，GCP1，LECT，LUCT，NAP1，IL-8，Interleukin-8，AMCF-I，SCYB8，Neutrophil-Activating Protein 1，B-ENAP，3-10C，K60，TSG-1，C-X-C Motif Chemokine Ligand 8，Monocyte-Derived Neutrophil Chemotactic Factor，Monocyte-Derived Neutrophil-Activating Peptide，Granulocyte Chemotactic Protein 1，Chemokine (C-X-C Motif) Ligand 8，(Ser-IL-8)72，Neutrophil-activating factor，MDNCF-c，C-X-C motif chemokine 8，Lymphocyte-derived neutrophil-activating factor，Protein 3-10C，IL-8(1-77)，NAF，GCP/IL-8 protein VI，GCP/IL-8 protein IV，IL8/NAP1 form I，MONAP，MDNCF-b，GCP/IL-8 protein V，CXCL8
Anzahl der inverkehr gebrachten Arzneimittel	1
Anzahl der klinischen Arzneimittel	6
Höchste Forschungs- und Entwicklungsphase	Approved

IL-8 Produktliste

Attribut
Protein (5)Kits (3)
Produktbibliothek
Online (7)In Forschung (1)
Spezies
Human (7)Rhesus macaque (1)
Etikett
His Tag (2)Fc Tag (1)His Tag & Avi Tag (1)- (3)Tag Free (1)
Marker
Unconjugated (4)Biotin-labeled (1)- (3)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT CRS-B004	Human	-	Human IL-8 ELISA Kit	In den Warenkorb legen
HOT IL8-H5217	Human	HEK293	Human IL-8 / CXCL8 Protein, premium grade	In den Warenkorb legen
HOT IL8-H52H3	Human	HEK293	Human IL-8 / CXCL8 Protein, His Tag	In den Warenkorb legen
HOT IL8-H82H3	Human	HEK293	Biotinylated Human IL-8 protein, His,Avitag™	In den Warenkorb legen
HOT IL8-C52H4	Rhesus macaque	HEK293	Rhesus macaque IL-8 / CXCL8 Protein, His Tag (MALS verified)	In den Warenkorb legen
CEA-C004	Human	-	Human IL-8 ELISA Kit, PRO	In den Warenkorb legen
FCSh-015	Human	-	Human IL-8 Detection Kit (Flow Cytometry Bead Assay)	Vorbestellung
IL8-H5258	Human	HEK293	Human IL-8 / CXCL8 Protein, Fc Tag	In den Warenkorb legen

Gesamtmenge8

Produktanfrage

IL-8 Molekülhintergrund

Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells. There are many receptors on the surface membrane capable of binding IL-8, the most frequently studied types are the G protein-coupled serpentine receptors CXCR1 and CXCR2. Expression and affinity for IL-8 differs between the two receptors (CXCR1 > CXCR2). IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.

IL-8 Molekülalias

CXCL8,GCP1,IL8,LECT,LUCT,LYNAP,MDNCF,MONAP,NAF,NAP-1

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Ensereptide	PXL-01	Phase 3 Clinical	Promore Pharma	Cicatrix; Post-surgical adhesions; Tissue Adhesions	Details
Cinainu		Phase 3 Clinical	Legacy Healthcare (Switzerland) Sa	Alopecia Areata	Details
Sodium Hypochlorite		Phase 3 Clinical		Cystic Fibrosis; Dental Pulp Necrosis; Fibrosis; Infections; Pain; Pain, Postoperative; Pulpitis	Details
Adakitug	BMS-986253; MDX-018	Phase 2 Clinical	Bristol-Myers Squibb Company, Genmab A/S, Medarex Inc	Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Coronavirus Disease 2019 (COVID-19); Hematologic Neoplasms; Melanoma; Myelodysplastic Syndromes; Neoplasms; Prostatic Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck	Details
AMY-109	AMY-109; AMY109	Phase 2 Clinical	Chugai Pharmaceutical Co Ltd	Endometriosis; Solid tumours	Details
AC-701	AC-701	Phase 2 Clinical	Twi Pharmaceuticals Inc	Exanthema; Rosacea	Details

Inverkehr gebrachte Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Frühestes Markenname	Frühestes Genehmigungsland	Früheste Indikation	Früheste Genehmigungsgesellschaft	Früheste Genehmigungsdatum	Indikationen	Klinische Studie
Mouse monoclonal antibody against human interleukin-8 cream		Approved	Dalian Asia Space Pharmaceutical Co Ltd, Dongguan Hongyuan Yishi Biotechnology Pharmaceutical Co Ltd	恩博克	Mainland China	Eczema; Psoriasis	Dalian Asia Space Pharmaceutical Co Ltd	2001-04-10	Eczema; Psoriasis	Details