IL-7 R alpha & TSLP R

IL-7 R alpha & TSLP R Molekülinformation

Englischer Name	Interleukin-7 receptor subunit alpha	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	8	Target-Alias	Interleukin-7 receptor subunit alpha，Interleukin 7 Receptor Isoform H5-6，CDw127，IL-7R subunit alpha，IL-7RA，IL-7 receptor subunit alpha，CD127 Antigen，IL-7R-Alpha，Interleukin 7 Receptor Alpha Chain，CD127，IL7RA，ILRA，Interleukin-7 Receptor alpha Subunit
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Englischer Name	Interleukin-7 receptor subunit alpha
Target-Alias	Interleukin-7 receptor subunit alpha，Interleukin 7 Receptor Isoform H5-6，CDw127，IL-7R subunit alpha，IL-7RA，IL-7 receptor subunit alpha，CD127 Antigen，IL-7R-Alpha，Interleukin 7 Receptor Alpha Chain，CD127，IL7RA，ILRA，Interleukin-7 Receptor alpha Subunit
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	8
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

IL-7 R alpha & TSLP R Produktliste

Attribut
Protein (3)Cell (1)Kits (1)
Produktbibliothek
Online (5)
Spezies
Human (4)Mouse (1)
Etikett
Fc Tag (3)- (2)
Marker
Unconjugated (3)- (2)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT CHEK-ATF045	Human	HEK293	Human TSLP R (Luc) HEK293 Reporter Cell	In den Warenkorb legen
HOT EP-129	Human	-	TSLP [Biotinylated] : IL-7Rα & TSLP R Inhibitor Screening ELISA Kit	In den Warenkorb legen
HOT ILR-H5255	Human	HEK293	Human IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag, low endotoxin (MALS verified)	In den Warenkorb legen
ILR-H525x	Human	HEK293	Human IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag	In den Warenkorb legen
ILR-M5257	Mouse	HEK293	Mouse IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag	In den Warenkorb legen

Gesamtmenge5

IL-7 R alpha & TSLP R Molekülhintergrund

TSLP is a pleiotropic cytokine originally characterized as a lymphocyte growth factor. Thymic stromal lymphopoietin (TSLP) is overexpressed in the airways of severe asthmatics and is an upstream cytokine that orchestrates inflammatory responses in asthma. Mouse TSLP exerts its biological activities by binding to a high-affinity heteromeric receptor complex composed of TSLPR and IL- 7 receptor and initiates signaling in cells co-expressing TSLPR and IL-7R.

IL-7 R alpha & TSLP R Molekülalias

IL7Ra,CD127,TSLP R,CRLF2,IL-XR,ILXR,p2RY8,CRLF2 fusion,TSLP receptor,TSLPR,CRL2,CRLF2Y,Cytokine receptor-like 2

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
CYT-107	CYT-107; CYT-99-007; rhIL-7	Phase 2 Clinical	Revimmune Inc	Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Catheter-Related Infections; Coronavirus Disease 2019 (COVID-19); Hepatitis B, Chronic; Hepatitis C; HIV Infections; Kidney Neoplasms; Leukemia, Myelogenous, Chronic; Leukemia, Myeloid, Acute; Lymphopenia; Metastatic breast cancer; Multiple Myeloma; Mycobacterium Infections, Nontuberculous; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neuroblastoma; Neuroectodermal Tumors, Primitive, Peripheral; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Sarcoma; Sarcoma, Kaposi; Sepsis; Shock, Septic; Skin Melanoma; T-Lymphocytopenia, Idiopathic CD4-Positive; Ureteral Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urologic Neoplasms	Details
Lusvertikimab	OSE-127; S-95011; Effi-7; OSE-217	Phase 2 Clinical	Effimune	Colitis, Ulcerative; Sjogren's Syndrome	Details
Efineptakin alfa	TJ-107; GX-I7; NT-I7	Phase 2 Clinical	Gannex Pharma Co Ltd	Astrocytoma; Breast Neoplasms; Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Coronavirus Disease 2019 (COVID-19); Esophageal Neoplasms; Glioblastoma; Glioma; Gliosarcoma; HIV Infections; Hypopharyngeal Neoplasms; Laryngeal Neoplasms; Leukoencephalopathy, Progressive Multifocal; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphopenia; Melanoma; Multiple Myeloma; Oropharyngeal Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Papillomavirus Infections; Plasmablastic Lymphoma; Prostatic Neoplasms, Castration-Resistant; Sarcoma, Kaposi; Small Cell Lung Carcinoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms	Details
ASP-9801	ASP-9801	Phase 1 Clinical	Astellas Pharma Inc	Neoplasm Metastasis; Neoplasms; Solid tumours	Details
PF-06342674	RN-168; PF-6342674; PF-06342674; ZB-168	Phase 1 Clinical	Pfizer Inc	Diabetes Mellitus, Type 1; Multiple Sclerosis	Details
CD19-IL7Ra CAR-T cells therapy (Chulalongkorn University)	CMD-63; CMD63	Phase 1 Clinical	Chulalongkorn University	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma	Details
Loco-regional B7H3 IL-7Ra CAR T Cell therapy(Chulalongkorn University)		Phase 1 Clinical	Chulalongkorn University, King Chulalongkorn Memorial Hospital	Brain Neoplasms; Diffuse Intrinsic Pontine Glioma; Neoplasms; Solid tumours	Details
MDK-703	MDK-703	Phase 1 Clinical	Medikine Inc	Solid tumours	Details