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IL-24

IL-24 Molekülinformation

Englischer NameInterleukin 24Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel1Target-AliasST16,Interleukin-24,IL24,MDA-7,Suppression of tumorigenicity 16 protein,IL-24,Interleukin 24,Suppression Of Tumorigenicity 16 (Melanoma Differentiation),Melanoma Differentiation-Associated Gene 7 Protein,IL-4-Induced Secreted Protein,MDA7,Melanoma Differentiation Association Protein 7,Melanocyte-Associated Mda-7,IL10B,C49A,FISP,MOB5,Mob-5
Höchste Forschungs- und EntwicklungsphasePhase 1 Clinical
Englischer NameInterleukin 24
Target-AliasST16,Interleukin-24,IL24,MDA-7,Suppression of tumorigenicity 16 protein,IL-24,Interleukin 24,Suppression Of Tumorigenicity 16 (Melanoma Differentiation),Melanoma Differentiation-Associated Gene 7 Protein,IL-4-Induced Secreted Protein,MDA7,Melanoma Differentiation Association Protein 7,Melanocyte-Associated Mda-7,IL10B,C49A,FISP,MOB5,Mob-5
Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel1
Höchste Forschungs- und EntwicklungsphasePhase 1 Clinical

IL-24 Produktliste

  • Attribut

    Protein (1)

  • Produktbibliothek

    Online (1)

  • Spezies

    Human (1)

  • Etikett

    His Tag (1)

  • Marker

    Unconjugated (1)

ProduktnummerSpeziesExpressionssystemProduktbeschreibungProteinstrukturReinheitEigenschaftenVorbestellen/Bestellen
IL4-H52H4
Human
HEK293
Human IL-24 Protein, His Tag (BLI verified)
In den Warenkorb legen
Gesamtmenge1
  • 1

IL-24 Molekülhintergrund

Interleukin-24 (IL-24, also known as melanoma differentiation-associated gene-7) belongs to the family of IL-10-related cytokines, which includes IL-10, -19, -20, -22, -24 and -26. Interleukin 24 signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. Upon binding to its receptors, IL-24 induces rapid activation of Stat-1 and Stat-3 transcription factors, which appear to play a role in cell survival and proliferation . Structurally and functionally, IL-24 is highly conserved across species.IL-24 has been shown to possess cancer-specific apoptosis-inducing activity, and has therefore been suggested as a potential anti-cancer agent.

IL-24 Molekülalias

Interleukin-24,IL-24,Melanoma differentiation-associated gene 7 protein,MDA-7,Suppression of tumorigenicity 16 protein,IL24,MDA7,ST16

Klinische Arzneimittelinformation

Englischer NameForschungscodeForschungsphaseFirmaIndikationenKlinische Studie
Interleukin 24 gene therapy (MultiVir)Ad-IL-24; Ad-IL24Phase 1 ClinicalMultivir IncHead and Neck Neoplasms; Melanoma
Details
  • Molekülinformation
  • Produktliste
  • Klinische Arzneimittelinformation
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