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Home PageAll MoleculesIL-17A & IL-17F
IL-17A & IL-17F
IL-17A & IL-17F Overview
| English Name | Interleukin-17F | Approved Drugs | 0 |
| Drugs in Clinical Trials | 5 | Target Synonym | Cytokine ML-1，Interleukin-17F，IL17F，Interleukin 17F，IL-17F，CANDF6，ML-1，ML1 |
| Highest Development Stage | NDA/BLA | ||
| English Name | Interleukin-17F |
| Target Synonym | Cytokine ML-1，Interleukin-17F，IL17F，Interleukin 17F，IL-17F，CANDF6，ML-1，ML1 |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 5 |
| Highest Development Stage | NDA/BLA |
IL-17A & IL-17F Product List
- Product Category
Protein (3)
- Product Status
Launched (3)
- Species
Human (2)Mouse (1)
- Tag
His Tag & Avi Tag (1)His Tag & Strep Tag (1)His Tag (1)
- Conjugate
Biotin-labeled (1)Unconjugated (2)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|---|
ILF-H52W6 |  Human | HEK293 | Human IL-17A&IL-17F Heterodimer Protein, Twin Strep&His Tag, low endotoxin (MALS verified) |  |  |  |
ILF-H82W1 | Human | HEK293 | Biotinylated Human IL-17A&IL-17F Protein, Avitag™,His Tag |  | | |
ILF-M52H3 |  Mouse | HEK293 | Mouse IL-17A&IL-17F Heterodimer Protein, His Tag (MALS verified) |  | |
Total: 3
- 1
IL-17A & IL-17F Background
Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
IL-17A & IL-17F Synonyms
IL-17A,Interleukin-17A,CTLA-8,IL-17,IL-17F,Interleukin-17F,Cytokine ML-1,IL17A＆IL17F
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| Sonelokimab | ALX-0761; MSB-0010841; M-1095 | Phase 3 Clinical | Ablynx Nv | Arthritis, Psoriatic; Hidradenitis Suppurativa; Psoriasis | Details |
| DMT-310 | DMT-310 | Phase 3 Clinical | Dermata | Acne Vulgaris; Rosacea | Details |
| ORKA-002 | ORKA-002; PR-029; ORKA-021 | Phase 2 Clinical | Paragon Therapeutics Inc | Arthritis, Psoriatic; Plaque psoriasis; Psoriasis | Details |
| PN-881 | PN-881 | Phase 1 Clinical | Protagonist Therapeutics Inc | Dermatitis; Psoriasis | Details |
| HY-1770 | HY-1770; HT-17; HT17; YF02; HT25; GH02; HY1770 | Phase 1 Clinical | Suzhou Pharmavan Co Ltd | Dermatitis, Atopic; Plaque psoriasis | Details |
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