IL-15 R alpha

IL-15 R alpha Molekülinformation

Englischer Name	Interleukin-15 receptor subunit alpha	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	13	Target-Alias	Interleukin 15 Receptor Alpha Isoform IC2，Interleukin 15 Receptor Alpha Isoform IC8，Interleukin 15 Receptor Alpha Isoform EM2，Interleukin-15 Receptor Subunit Alpha，Interleukin 15 Receptor Alpha Isoform IC4，Interleukin 15 Receptor Alpha Isoform IC5，Interleukin 15 Receptor Alpha Isoform IC7，IL15RA，CD215，IL-15RA，IL-15 Receptor Subunit Alpha，CD215 Antigen，Interleukin 15 Receptor Subunit Alpha，Interleukin 15 Receptor Alpha Isoform IC6，Interleukin 15 Receptor， Alpha，Interleukin 15 Receptor Alpha Isoform IC3，sIL-15 receptor subunit alpha，IL-15R-Alpha，Interleukin-15 Receptor alpha Subunit，sIL-15RA，sIL-15R-alpha
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Englischer Name	Interleukin-15 receptor subunit alpha
Target-Alias	Interleukin 15 Receptor Alpha Isoform IC2，Interleukin 15 Receptor Alpha Isoform IC8，Interleukin 15 Receptor Alpha Isoform EM2，Interleukin-15 Receptor Subunit Alpha，Interleukin 15 Receptor Alpha Isoform IC4，Interleukin 15 Receptor Alpha Isoform IC5，Interleukin 15 Receptor Alpha Isoform IC7，IL15RA，CD215，IL-15RA，IL-15 Receptor Subunit Alpha，CD215 Antigen，Interleukin 15 Receptor Subunit Alpha，Interleukin 15 Receptor Alpha Isoform IC6，Interleukin 15 Receptor， Alpha，Interleukin 15 Receptor Alpha Isoform IC3，sIL-15 receptor subunit alpha，IL-15R-Alpha，Interleukin-15 Receptor alpha Subunit，sIL-15RA，sIL-15R-alpha
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	13
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

IL-15 R alpha Produktliste

Attribut
Protein (6)
Produktbibliothek
Online (6)
Spezies
Human (5)Mouse (1)
Etikett
Fc Tag (4)Fc Tag & Avi Tag (1)His Tag & Avi Tag (1)
Marker
Unconjugated (2)Biotin-labeled (2)FITC Labeled (1)PE Labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT ILA-H5253	Human	HEK293	Human IL-15 R alpha / CD215 Protein, Fc Tag, low endotoxin (MALS verified)	In den Warenkorb legen
HOT ILA-H82F4	Human	HEK293	Biotinylated Human IL-15 R alpha / CD215 Protein, Fc,Avitag™ (MALS verified)	In den Warenkorb legen
HOT ILA-HF255	Human	HEK293	FITC-Labeled Human IL-15 R alpha / CD215 Protein, Fc Tag (MALS verified)	In den Warenkorb legen
HOT ILA-HP2F6	Human	HEK293	PE-Labeled Human IL-15 R alpha / CD215 Protein, Fc Tag (Site-specific conjugation)	In den Warenkorb legen
ILA-H82E5	Human	HEK293	Biotinylated Human IL-15 R alpha Protein, His,Avitag™ (MALS verified)	In den Warenkorb legen
ILA-M5253	Mouse	HEK293	Mouse IL-15 R alpha / CD215 Protein, Fc Tag	In den Warenkorb legen

Gesamtmenge6

IL-15 R alpha Molekülhintergrund

IL15R is a heterotrimer of IL15RA, IL2RB and IL2RG. IL-15RA, also known as CD215, IL-15 R alpha, is a widely expressed 60 kDa transmembrane glycoprotein. High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. An interleukin (IL)-15 superagonist/IL-15 receptor α fusion complex (IL-15SA/IL-15RA; ALT-803) activates the IL-15 receptor on CD8 T cells and NK cells, and has shown significant anti-tumor. Signal transduction involves SYK. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures.

IL-15 R alpha Molekülalias

IL-15 R alpha,CD215,IL15RA,IL-15RA,IL-15R-alpha

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
SHR-1501	SHR-1501	Phase 3 Clinical	Jiangsu Hengrui Medicine Co Ltd	Neoplasms; Urinary Bladder Neoplasms	Details
Avipendekin pegol	NKTR-255	Phase 2 Clinical	Nektar Therapeutics	Carcinoma, Non-Small-Cell Lung; Carcinoma, Transitional Cell; Colorectal Neoplasms; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Multiple Myeloma; Squamous Cell Carcinoma of Head and Neck	Details
ASKG-915	ASKG-915	Phase 2 Clinical	Askgene Pharma	Colorectal Neoplasms; Neoplasms; Solid tumours	Details
VG-201	VG-201	Phase 2 Clinical	ViroGin Biotech Ltd	Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Esophageal Neoplasms; Neoplasms; Solid tumours; Stomach Neoplasms	Details
FL115	FL-115; FL115	Phase 2 Clinical	Suzhou Forlongbiotech Co Ltd	Solid tumours; Urinary Bladder Neoplasms	Details
Efbalropendekin alfa	XmAb-24306; RG-6323; RO-7310729; XmAb-306	Phase 1 Clinical	Xencor Inc	Multiple Myeloma; Solid tumours	Details
BJ-001(Boji Biomedical Technology)	BJ-001	Phase 1 Clinical	Boji Biomedical Technology (Hangzhou) Co Ltd	Communicable Diseases; Neoplasm Metastasis; Solid tumours	Details
ASKG-315	ASKG-315; ASKG-215b; ASKG-215β	Phase 1 Clinical	Askgene Pharma	Neoplasms; Solid tumours	Details
VG-203	VG-203; VG2062; VG-2062	Phase 1 Clinical	Fenojian Biotechnology (Nantong) Co Ltd, Shanghai Funuojian Biotechnology Co Ltd, Virogin Biotech (Shenzhen) Ltd, ViroGin Biotech Ltd	Breast Neoplasms; Carcinoma, Renal Cell; Ovarian Neoplasms; Solid tumours	Details
BAT-7205	BAT7205; BAT-7205	Phase 1 Clinical	Bio-Thera Solutions Ltd	Neoplasm Metastasis; Solid tumours	Details
RC-198	RC-198	Phase 1 Clinical		Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Colorectal Neoplasms; Melanoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck	Details
QL-415	QL-415	Phase 1 Clinical	Qlsf Biotherapeutics Inc	Neoplasms	Details
Recombinant human interleukin 15(Beijing Kawin)		Phase 1 Clinical	Beijing Kawin Technology Share-Holding Co Ltd	Solid tumours	Details