IL-13 R alpha 1

IL-13 R alpha 1 Molekülinformation

Englischer Name	Interleukin-13 receptor subunit alpha-1	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1	Target-Alias	IL-13 receptor subunit alpha-1，IL-13R subunit alpha-1，IL-13R-alpha-1，IL-13RA1，Cancer/testis antigen 19，CD213a1，Interleukin 13 Receptor Subunit Alpha 1，CD213a1 Antigen，Interleukin-13 Receptor Subunit Alpha-1，Interleukin 13 Receptor， Alpha 1，IL-13 Receptor Subunit Alpha-1，IL13 Receptor Alpha-1 Chain，Cancer/Testis Antigen 19，IL-13R Subunit Alpha-1，IL-13Ra，NR4，IL-13R-Alpha-1，CD213A1，IL13RA1，IL13RA
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Englischer Name	Interleukin-13 receptor subunit alpha-1
Target-Alias	IL-13 receptor subunit alpha-1，IL-13R subunit alpha-1，IL-13R-alpha-1，IL-13RA1，Cancer/testis antigen 19，CD213a1，Interleukin 13 Receptor Subunit Alpha 1，CD213a1 Antigen，Interleukin-13 Receptor Subunit Alpha-1，Interleukin 13 Receptor， Alpha 1，IL-13 Receptor Subunit Alpha-1，IL13 Receptor Alpha-1 Chain，Cancer/Testis Antigen 19，IL-13R Subunit Alpha-1，IL-13Ra，NR4，IL-13R-Alpha-1，CD213A1，IL13RA1，IL13RA
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

IL-13 R alpha 1 Produktliste

Attribut
Protein (6)
Produktbibliothek
Online (6)
Spezies
Human (3)Mouse (2)Cynomolgus (1)
Etikett
His Tag (3)Fc Tag (1)Fc Tag & Avi Tag (1)His Tag & Avi Tag (1)
Marker
Unconjugated (4)Biotin-labeled (2)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT IL1-H5224	Human	HEK293	Human IL-13 R alpha 1 Protein, His Tag (MALS & SPR verified)	In den Warenkorb legen
HOT IL1-H82E8	Human	HEK293	Biotinylated Human IL-13 R alpha 1 Protein, His,Avitag™ (MALS & SPR verified)	In den Warenkorb legen
HOT IL1-H82F6	Human	HEK293	Biotinylated Human IL-13 R alpha 1 Protein, Fc,Avitag™ (SPR verified)	In den Warenkorb legen
IL1-M5258	Mouse	HEK293	Mouse IL-13 R alpha 1 Protein, Fc Tag	In den Warenkorb legen
IL1-M52H7	Mouse	HEK293	Mouse IL-13 R alpha 1 Protein, His Tag	In den Warenkorb legen
IL1-C52H8	Cynomolgus	HEK293	Cynomolgus IL-13 R alpha 1 Protein, His Tag	In den Warenkorb legen

Gesamtmenge6

IL-13 R alpha 1 Molekülhintergrund

Interleukin 13 receptor, alpha 1 is also known as IL13RA1, NR4 and CD213A1 (cluster of differentiation 213A1), The IL13 Rα1 cDNA encodes a 427 amino acid (aa) residue precursor protein with a putative 21 aa residue signal peptide, a 324 aa residue extracellular domain, a 23 aa residue transmembrane region and a 59 aa residue cytoplasmic tail. Human and mouseIL13Rα1 share 76% aa sequence identity. IL13RA1 is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.