IGF-II R

IGF-II R Molekülinformation

Englischer Name	Insulin-like growth factor II receptor	Anzahl der inverkehr gebrachten Arzneimittel	1
Anzahl der klinischen Arzneimittel	0	Target-Alias	Insulin-like growth factor 2 receptor，IGF-II receptor，CD222，Insulin Like Growth Factor 2 Receptor，M6P/IGF2R，M6P/IGF2 receptor，CI Man-6-P receptor，Insulin-like growth factor II receptor，IGF2R，300 KDa Mannose 6-Phosphate Receptor，MPR 300，MPRI，Cation-Independent Mannose-6-Phosphate Receptor，Cation-Independent Mannose-6 Phosphate Receptor，CD222 Antigen，CI-M6PR，MPR300，CI-MPR，CIMPR，M6P-R，MPR1，M6PR，Receptor， IGF Type 2
Höchste Forschungs- und Entwicklungsphase	Approved

Englischer Name	Insulin-like growth factor II receptor
Target-Alias	Insulin-like growth factor 2 receptor，IGF-II receptor，CD222，Insulin Like Growth Factor 2 Receptor，M6P/IGF2R，M6P/IGF2 receptor，CI Man-6-P receptor，Insulin-like growth factor II receptor，IGF2R，300 KDa Mannose 6-Phosphate Receptor，MPR 300，MPRI，Cation-Independent Mannose-6-Phosphate Receptor，Cation-Independent Mannose-6 Phosphate Receptor，CD222 Antigen，CI-M6PR，MPR300，CI-MPR，CIMPR，M6P-R，MPR1，M6PR，Receptor， IGF Type 2
Anzahl der inverkehr gebrachten Arzneimittel	1
Anzahl der klinischen Arzneimittel	0
Höchste Forschungs- und Entwicklungsphase	Approved

IGF-II R Produktliste

Attribut
Protein (2)
Produktbibliothek
Online (2)
Spezies
Human (2)
Etikett
His Tag (2)
Marker
Unconjugated (2)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
IGR-H52H4	Human	HEK293	Human IGF-II R (43-1365) Protein, His Tag (MALS verified)				In den Warenkorb legen
IGR-H53H3	Human	CHO	Human IGF-II R Protein, His Tag (MALS verified)				In den Warenkorb legen

Gesamtmenge2

IGF-II R Molekülhintergrund

IGF2R, also known as the cation-independent mannose-6-phosphate receptor, is found ubiquitously in human tissues with a truncated soluble form of the receptor present in the circulation. Full-length, 300-kDa, IGF2R comprises a large N-terminal extracellular region of 15 homologous domains, a single membrane-spanning region and a small cytoplasmic tail. In addition to IGF-II binding, major IGF2R functions include sorting newly synthesized lysosomal enzymes and endocytosis of extracellular lysosomal enzymes. To perform these disparate functions, the extracellular region contains binding sites for IGF-II and phosphomannosyl residues

IGF-II R Molekülalias

Cation-independent mannose-6-phosphate receptor,CI Man-6-P receptor,CI-MPR,M6PR,300 kDa mannose 6-phosphate receptor (MPR 300),Insulin-like growth factor 2 receptor,Insulin-like growth factor II receptor (IGF-II receptor),M6P/IGF2 receptor (M6P/IGF2R),CD2

Inverkehr gebrachte Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Frühestes Markenname	Frühestes Genehmigungsland	Früheste Indikation	Früheste Genehmigungsgesellschaft	Früheste Genehmigungsdatum	Indikationen	Klinische Studie
Avalglucosidase alfa	neoGAA; GZ-402666; Neo-rhGAA; NeoGAA	Approved	Genzyme Corp	Nexviazyme, Nexviadyme, 耐而赞	United States	Glycogen Storage Disease Type II	Genzyme Corp	2021-08-06	Glycogen Storage Disease Type II	Details