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HSP90AA1

HSP90AA1 Overview

English Name	Heat shock protein HSP 90-alpha	Approved Drugs	1
Drugs in Clinical Trials	0	Target Synonym	Heat Shock Protein 90kDa Alpha (Cytosolic)， Class A Member 1，Heat Shock 90kDa Protein 1， Alpha，Heat Shock 90kD Protein 1， Alpha，HSP 86，HSP90A，HSPC1，Heat Shock Protein 90kDa Alpha Family Class A Member 1，Epididymis Secretory Sperm Binding Protein Li 65p，Epididymis Luminal Secretory Protein 52，Heat Shock 90kD Protein 1， Alpha-Like 4，Heat Shock 90kD Protein， Alpha-Like 4，HEL-S-65p，FLJ31884，HSPCAL1，HSPCAL4，HSP89A，HSP90N，Hsp103，Hsp89，Hsp90，EL52，HSPN，LAP2，Heat shock protein HSP 90-alpha，HSP86，LPS-associated protein 2，HSPCA，HSP90AA1，Heat Shock Protein 90 Alpha Family Class A Member 1，Renal carcinoma antigen NY-REN-38，Heat shock 86 kDa，Lipopolysaccharide-associated protein 2，LAP-2
Highest Development Stage	Approved

English Name	Heat shock protein HSP 90-alpha
Target Synonym	Heat Shock Protein 90kDa Alpha (Cytosolic)， Class A Member 1，Heat Shock 90kDa Protein 1， Alpha，Heat Shock 90kD Protein 1， Alpha，HSP 86，HSP90A，HSPC1，Heat Shock Protein 90kDa Alpha Family Class A Member 1，Epididymis Secretory Sperm Binding Protein Li 65p，Epididymis Luminal Secretory Protein 52，Heat Shock 90kD Protein 1， Alpha-Like 4，Heat Shock 90kD Protein， Alpha-Like 4，HEL-S-65p，FLJ31884，HSPCAL1，HSPCAL4，HSP89A，HSP90N，Hsp103，Hsp89，Hsp90，EL52，HSPN，LAP2，Heat shock protein HSP 90-alpha，HSP86，LPS-associated protein 2，HSPCA，HSP90AA1，Heat Shock Protein 90 Alpha Family Class A Member 1，Renal carcinoma antigen NY-REN-38，Heat shock 86 kDa，Lipopolysaccharide-associated protein 2，LAP-2
Approved Drugs	1
Drugs in Clinical Trials	0
Highest Development Stage	Approved

HSP90AA1 Product List

Product Category
Protein (1)
Product Status
Launched (1)
Species
Human (1)
Tag
GST Tag (1)
Conjugate
Unconjugated (1)

Cat. No.	Species	Host	Product Description	Structure	Purity	Feature
HS1-H513x	Human	E. coli	Human HSP90AA1 / HSP86 Protein, GST Tag

Total: 1

HSP90AA1 Background

Heat shock protein HSP 90-alpha (HSP90AA1 or HSP90A) is also known as Heat shock 86 kDa (HSP 86 or HSP86), Renal carcinoma antigen NY-REN-38, HSPC1, HSPCA, EL52, HSP89A, HSP90N, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2, which belongs to the heat shock protein 90 family. HSP90AA1 undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. HSP90AA1 interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

HSP90AA1 Synonyms

HSP90AA1,HSP90A,HSP 86,HSP86,HSPC1,HSPCA,EL52,HSP89A,HSP90N,HSPCAL1,HSPCAL4,HSPN,Hsp89,Hsp90,LAP2

Marketed Drug Information

English Name	Research Code	Highest Development Stage	Company	Earliest Brand Name	Earliest Approval Country	Earliest Indication	Earliest Approval Company	Earliest Approval Date	Indication	Clinical Trial
Pimitespib	TAS-116	Approved	Otsuka Pharmaceutical Co Ltd, Taiho Pharmaceutical Co Ltd	Jeselhy, ジェセリ	Japan	Gastrointestinal Stromal Tumors	Taiho Pharmaceutical Co Ltd	2022-08-01	Biliary Tract Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Esophageal Neoplasms; Gastrointestinal Stromal Tumors; Head and Neck Neoplasms; Sarcoma, Alveolar Soft Part; Solid tumours; Stomach Neoplasms	Details