GPR75

GPR75 Product List

  • Product Category

    Cell (1)Protein (2)

  • Product Status

    Launched (3)

  • Species

    Human (3)

  • Tag

    - (2)His Tag & Flag Tag (1)

  • Conjugate

    - (1)Unconjugated (2)

GPR75 Background

G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
bbT-369bbT-369Phase 2 ClinicalBluebird Bio IncLymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin
Details

Product Reviews

  • H***e2025-11-02
    0People Like
    We verified that the cell line shows strong GPR75 expression by flow cytometry. The Acro team was very responsive and provided clear, helpful answers to our technical questions about the cell line’s characteristics.
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