GM-CSF R alpha

GM-CSF R alpha Molekülinformation

Englischer Name	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	4	Target-Alias	GM-CSF-R-alpha，GMCSFR-alpha，GMR-alpha，CD116，Colony Stimulating Factor 2 Receptor Subunit Alpha，Colony Stimulating Factor 2 Receptor， Alpha， Low-Affinity (Granulocyte-Macrophage)，CSF2R，CSF2RAX，CSF2RAY，CSF2RX，CSF2RY，GM-CSF Receptor Alpha Subunit，GMCSFR，GMR，Granulocyte-Macrophage Colony-Stimulating Factor Receptor Alpha Chain，SMDP4，Colony Stimulating Factor 2 Receptor Alpha Subunit，CDw116，CD116 Antigen，Alpha-GM-CSF Receptor，AlphaGMR
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Englischer Name	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
Target-Alias	GM-CSF-R-alpha，GMCSFR-alpha，GMR-alpha，CD116，Colony Stimulating Factor 2 Receptor Subunit Alpha，Colony Stimulating Factor 2 Receptor， Alpha， Low-Affinity (Granulocyte-Macrophage)，CSF2R，CSF2RAX，CSF2RAY，CSF2RX，CSF2RY，GM-CSF Receptor Alpha Subunit，GMCSFR，GMR，Granulocyte-Macrophage Colony-Stimulating Factor Receptor Alpha Chain，SMDP4，Colony Stimulating Factor 2 Receptor Alpha Subunit，CDw116，CD116 Antigen，Alpha-GM-CSF Receptor，AlphaGMR
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	4
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

GM-CSF R alpha Produktliste

Attribut
Protein (3)
Produktbibliothek
Online (3)
Spezies
Human (2)Mouse (1)
Etikett
His Tag (2)Fc Tag (1)
Marker
Unconjugated (3)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT GRA-H52H7	Human	HEK293	Human GM-CSF R alpha Protein, His Tag (SPR verified)	In den Warenkorb legen
GRA-H5255	Human	HEK293	Human GM-CSF R alpha Protein, Fc Tag	In den Warenkorb legen
GMA-M52H3	Mouse	HEK293	Mouse GM-CSF R alpha Protein, His Tag	In den Warenkorb legen

Gesamtmenge3

GM-CSF R alpha Molekülhintergrund

GM-CSF R alpha(Granulocyte-macrophage colony-stimulating factor receptor subunit alpha) is also known as CSF2RA, CD116, GMR-alpha. Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder of pulmonary surfactant accumulation and hypoxemic respiratory failure caused by mutations in CSF2RA (encoding the granulocyte/macrophage colony-stimulating factor [GM-CSF] receptor α-chain [CD116]), which results in reduced GM-CSF-dependent pulmonary surfactant clearance by alveolar macrophages.

GM-CSF R alpha Molekülalias

GM-CSF R alpha,GM-CSF-R-alpha,GMCSFR-alpha,GMR-alpha,CSF2RA,CSF2R,CSF2RY,CDw116,CD116

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Mavrilimumab	CAM-3001; KPL-301; GM-CSFR; CAM3001	Phase 3 Clinical	Csl Ltd	Arthritis, Rheumatoid; Coronavirus Disease 2019 (COVID-19); Giant Cell Arteritis; Pneumonia	Details
Anti-GMR CAR T-cell Therapy		Phase 2 Clinical	Kyoto Prefectural University Of Medicine, Shinshu University School of Medicine	Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Juvenile	Details
CSF2RA gene-corrected macrophages(University of South Florida)		Phase 2 Clinical	Russian Academy Of Medical Sciences	Pulmonary Alveolar Proteinosis	Details
STSA-1005	STSA-1005; STSA1005	Phase 1 Clinical	Staidson(Beijing) Biopharmaceuticals Co Ltd	Coronavirus Disease 2019 (COVID-19)	Details