GITR Ligand

GITR Ligand Molekülinformation

Englischer Name	Tumor necrosis factor ligand superfamily member 18	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	0	Target-Alias	AITRL，GITRL，TL6，UNQ149，PRO175，Glucocorticoid-induced TNF-related ligand，hGITRL，Activation-inducible TNF-related ligand
Höchste Forschungs- und Entwicklungsphase	Preclinical

Englischer Name	Tumor necrosis factor ligand superfamily member 18
Target-Alias	AITRL，GITRL，TL6，UNQ149，PRO175，Glucocorticoid-induced TNF-related ligand，hGITRL，Activation-inducible TNF-related ligand
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	0
Höchste Forschungs- und Entwicklungsphase	Preclinical

GITR Ligand Produktliste

Attribut
Protein (6)
Produktbibliothek
Online (6)
Spezies
Human (5)Mouse (1)
Etikett
Fc Tag (3)Avi Tag & Fc Tag (1)His Tag (2)
Marker
Unconjugated (5)Biotin-labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT GIL-H5249	Human	HEK293	Human GITR Ligand / TNFSF18 Protein, His Tag	In den Warenkorb legen
HOT GIL-H524a	Human	HEK293	Human GITR Ligand / TNFSF18 Protein, His Tag, active trimer (MALS verified)	In den Warenkorb legen
HOT GIL-H5263	Human	HEK293	Human GITR Ligand / TNFSF18 Protein, Fc Tag, active trimer (MALS verified)	In den Warenkorb legen
GIL-H526a	Human	HEK293	Human GITR Ligand / TNFSF18 Protein, Fc Tag	In den Warenkorb legen
GIL-H82F8	Human	HEK293	Biotinylated Human GITR Ligand / TNFSF18 Protein, Avitag™,Fc Tag	In den Warenkorb legen
GIL-M526x	Mouse	HEK293	Mouse GITR Ligand / TNFSF18 Protein, Fc Tag	In den Warenkorb legen

Gesamtmenge6

GITR Ligand Molekülhintergrund

Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.