GITR

GITR Molekülinformation

Englischer Name	Glucocorticoid-induced tumor necrosis factor receptor-related protein	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	4	Target-Alias	TNFRSF18，TNF Receptor Superfamily Activation-Inducible Protein，ENERGEN，GITR-D，Tumor Necrosis Factor Receptor Superfamily Member 18，CD357 Antigen，Activation-Inducible TNFR Family Receptor，AITR，CD357，GITR，Glucocorticoid-Induced TNFR-Related Protein，Tumor Necrosis Factor Receptor Superfamily， Member 18，TNF Receptor Superfamily Member 18
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Englischer Name	Glucocorticoid-induced tumor necrosis factor receptor-related protein
Target-Alias	TNFRSF18，TNF Receptor Superfamily Activation-Inducible Protein，ENERGEN，GITR-D，Tumor Necrosis Factor Receptor Superfamily Member 18，CD357 Antigen，Activation-Inducible TNFR Family Receptor，AITR，CD357，GITR，Glucocorticoid-Induced TNFR-Related Protein，Tumor Necrosis Factor Receptor Superfamily， Member 18，TNF Receptor Superfamily Member 18
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	4
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

GITR Produktliste

Attribut
Protein (7)
Produktbibliothek
Online (7)
Spezies
Human (4)Canine (1)Mouse (2)
Etikett
His Tag (3)Fc Tag (1)Fc Tag & Avi Tag (1)His Tag & Avi Tag (2)
Marker
Unconjugated (4)Biotin-labeled (3)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT GIR-H5228	Human	HEK293	Human GITR / TNFRSF18 Protein, His Tag, low endotoxin (MALS verified)	In den Warenkorb legen
HOT GIR-H5254	Human	HEK293	Human GITR / TNFRSF18 Protein, Fc Tag, low endotoxin	In den Warenkorb legen
GIR-H82E5	Human	HEK293	Biotinylated Human GITR / TNFRSF18 Protein, His,Avitag™ (MALS verified)	In den Warenkorb legen
GIR-H82F7	Human	HEK293	Biotinylated Human GITR / TNFRSF18 Protein, Fc,Avitag™	In den Warenkorb legen
GIR-M52H3	Mouse	HEK293	Mouse GITR / TNFRSF18 Protein, His Tag	In den Warenkorb legen
GIR-M82E3	Mouse	HEK293	Biotinylated Mouse GITR / TNFRSF18 Protein, His,Avitag™ (MALS verified)	In den Warenkorb legen
GIR-C52H6	Canine	HEK293	Canine GITR / TNFRSF18 Protein, His Tag	In den Warenkorb legen

Gesamtmenge7

GITR Molekülhintergrund

Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

GITR Molekülalias

AITR,GITR,TNFRSF18,CD357

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
BMS-986156	BMS-986156	Phase 2 Clinical	Bristol-Myers Squibb Company	Liver Neoplasms; Lung Neoplasms; Neoplasms; Solid tumours; Thoracic Neoplasms	Details
Ragifilimab	INCAGN-1876; INCAGN-01876; AGEN-1876; CM-701	Phase 2 Clinical	Agenus Inc, Ludwig Institute For Cancer Research	Neoplasm Metastasis; Neoplasms	Details
Anti-GITR antibody (BMS)		Phase 1 Clinical	Bristol-Myers Squibb Company	Neoplasms	Details
IBI-102	IBI102; IBI-102	Phase 1 Clinical		Neoplasms	Details

Produktrezensionen

1***32019-09-27
1Menschen mögen
Human GITR / TNFRSF18 Protein, His Tag, low endotoxin (MALS verified)
I have been using Acro's products for a long time. Whenever there is some concerns on product or technical support is needed, it always gets solved in time. I used the GITR protein for SPR experiments. I have done 6 concentration gradients, and the fitted curve was still very good. The data also met my expectations. I hope we will continue having a good cooperation with ACRO moving forward.