Frizzled-4

Frizzled-4 Molekülinformation

Englischer Name	Frizzled-4	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1	Target-Alias	hFz4，FzE4，CD344，Frizzled 4， Seven Transmembrane Spanning Receptor，Fz-4，Frizzled Family Receptor 4，EVR1，Frizzled (Drosophila) Homolog 4，Frizzled Homolog 4 (Drosophila)，Exudative Vitreoretinopathy 1，WNT Receptor Frizzled-4，Frizzled Homolog 4，CD344 Antigen，FZD4S，FEVR，GPCR，Fz4
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Englischer Name	Frizzled-4
Target-Alias	hFz4，FzE4，CD344，Frizzled 4， Seven Transmembrane Spanning Receptor，Fz-4，Frizzled Family Receptor 4，EVR1，Frizzled (Drosophila) Homolog 4，Frizzled Homolog 4 (Drosophila)，Exudative Vitreoretinopathy 1，WNT Receptor Frizzled-4，Frizzled Homolog 4，CD344 Antigen，FZD4S，FEVR，GPCR，Fz4
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Frizzled-4 Produktliste

Attribut
Protein (2)
Produktbibliothek
Online (2)
Spezies
Human (2)
Etikett
Fc Tag (1)His Tag & Avi Tag (1)
Marker
Unconjugated (1)Biotin-labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
FZ4-H5250	Human	HEK293	Human Frizzled-4 / FZD4 Protein, Fc Tag				In den Warenkorb legen
FZ4-H82E3	Human	HEK293	Biotinylated Human Frizzled-4 / FZD4 Protein, His,Avitag™ (MALS verified)				In den Warenkorb legen

Gesamtmenge2

Frizzled-4 Molekülhintergrund

Frizzled-4 (FZD4) is also known as FzE4, CD344, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD4 contains one FZ (frizzled) domain. FZD4 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD4 interacts with MAGI3 and norrin (NDP).