FGF acidic

FGF acidic Molekülinformation

Englischer Name	Fibroblast growth factor 1	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	2	Target-Alias	Fibroblast Growth Factor 1 (Acidic)，HBGF1，Acidic fibroblast growth factor，Heparin-binding growth factor 1，HBGF-1，Endothelial cell growth factor，FGF1，Fibroblast Growth Factor 1，Endothelial Cell Growth Factor， Alpha，Endothelial Cell Growth Factor， Beta，FGF-1，AFGF，FGFA，ECGF，Beta-Endothelial Cell Growth Factor，ECGF-Beta，FGF-Alpha，GLIO703，ECGFA，ECGFB
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Englischer Name	Fibroblast growth factor 1
Target-Alias	Fibroblast Growth Factor 1 (Acidic)，HBGF1，Acidic fibroblast growth factor，Heparin-binding growth factor 1，HBGF-1，Endothelial cell growth factor，FGF1，Fibroblast Growth Factor 1，Endothelial Cell Growth Factor， Alpha，Endothelial Cell Growth Factor， Beta，FGF-1，AFGF，FGFA，ECGF，Beta-Endothelial Cell Growth Factor，ECGF-Beta，FGF-Alpha，GLIO703，ECGFA，ECGFB
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	2
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

FGF acidic Produktliste

Attribut
Protein (1)
Produktbibliothek
Online (1)
Spezies
Human (1)
Etikett
Tag Free (1)
Marker
Unconjugated (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
AFF-H4116	Human	E. coli	Human FGF acidic Protein, Tag Free				In den Warenkorb legen

Gesamtmenge1

FGF acidic Molekülhintergrund

Heparin-binding growth factor 1 is a protein that in humans is encoded by the FGF1 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF acidic is a potent growth factor for fibroblasts and endothelial cells. FGF acidic is involved in wound repair, angiogenesis, and development. FGF acidic is secreted from cells via an endoplasmic reticulum/Golgi independent mechanism. The ability of FGF acidic to bind to heparin sulfate is required for its ability to interact with FGF receptors and induce signaling. There are four distinct FGF receptors and each has multiple splice variants. FGF acidic binds with high affinity to many, but not all, FGFRs. Signaling cascades activated through FGF basic binding to FGFR include the ras-raf-MAPK, PLCγ/PKC, and PI3K/Akt pathways.

FGF acidic Molekülalias

FGF1,AFGF,ECGF,ECGF-beta,ECGFA,ECGFB,FGF-alpha,FGFA,GLIO703,HBGF1

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Muparfostat sodium	PI-88	Phase 3 Clinical	Australian National University	Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Liver Neoplasms; Lung Neoplasms; Melanoma; Neoplasms; Prostatic Neoplasms; Skin Melanoma; Solid tumours	Details
TTHX-1114	TTHX-1114; NM-141; NM141; TTHX1114	Phase 2 Clinical	Florida State University	Corneal Diseases; Corneal Dystrophies, Hereditary; Fuchs' Endothelial Dystrophy; Vascular Diseases	Details