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StartseiteAlle MoleküleENPP-2
ENPP-2
ENPP-2 Molekülinformation
| Englischer Name | Ectonucleotide pyrophosphatase/phosphodiesterase 2 | Anzahl der inverkehr gebrachten Arzneimittel | 0 |
| Anzahl der klinischen Arzneimittel | 9 | Target-Alias | EC:3.1.4.39，ATX，Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 2，Phosphodiesterase I/Nucleotide Pyrophosphatase 2，Plasma Lysophospholipase D，Autotaxin-T，EC 3.1.4.39，PD-IALPHA，ATX-X，NPP2，E-NPP 2，Autotaxin，ENPP2，PDNP2，Ectonucleotide Pyrophosphatase/Phosphodiesterase 2，Extracellular Lysophospholipase D，LysoPLD |
| Höchste Forschungs- und Entwicklungsphase | Phase 2 Clinical | ||
| Englischer Name | Ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| Target-Alias | EC:3.1.4.39，ATX，Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 2，Phosphodiesterase I/Nucleotide Pyrophosphatase 2，Plasma Lysophospholipase D，Autotaxin-T，EC 3.1.4.39，PD-IALPHA，ATX-X，NPP2，E-NPP 2，Autotaxin，ENPP2，PDNP2，Ectonucleotide Pyrophosphatase/Phosphodiesterase 2，Extracellular Lysophospholipase D，LysoPLD |
| Anzahl der inverkehr gebrachten Arzneimittel | 0 |
| Anzahl der klinischen Arzneimittel | 9 |
| Höchste Forschungs- und Entwicklungsphase | Phase 2 Clinical |
ENPP-2 Produktliste
- Attribut
Protein (1)
- Produktbibliothek
Online (1)
- Spezies
Human (1)
- Etikett
His Tag (1)
- Marker
Unconjugated (1)
| Produktnummer | Spezies | Expressionssystem | Produktbeschreibung | Proteinstruktur | Reinheit | Eigenschaften | Vorbestellen/Bestellen |
|---|---|---|---|---|---|---|---|
 Human | HEK293 | Human ENPP-2 / Autotaxin Protein, His Tag (active enzyme) |  |  |  In den Warenkorb legen |
Gesamtmenge1
- 1
ENPP-2 Molekülhintergrund
Autotaxin also known as ectonucleotide pyrophosphatase / phosphodiesterase family member 2 (E-NPP 2 or ENPP2), Extracellular lysophospholipase D (LysoPLD), Autotaxin (ATX or ATX-X), which belongs to the nucleotide pyrophosphatase / phosphodiesterase family. ENPP2 contains two SMB (somatomedin-B) domains. ENPP2 hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. ENPP2 can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. ENPP2 stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein.
ENPP-2 Molekülalias
ENPP-2,E-NPP 2,Autotaxin,LysoPLD,ATX,PDNP2,ATX-X,NPP2,PD-IALPHA
Klinische Arzneimittelinformation
| Englischer Name | Forschungscode | Forschungsphase | Firma | Indikationen | Klinische Studie |
|---|---|---|---|---|---|
| BBT-877 | BBT-877 | Phase 2 Clinical | Legochem | Idiopathic Pulmonary Fibrosis | Details |
| Cambritaxestat | CRT-0273750; IOA-289 | Phase 2 Clinical | Cancer Research Technology, Merck & Co | Pancreatic Neoplasms; Solid tumours | Details |
| HRS-9813 | HRS-9813; HRS9813 | Phase 2 Clinical | Guangdong Hengrui Pharmaceutical Co Ltd | Idiopathic Pulmonary Fibrosis; Pulmonary Fibrosis | Details |
| HW-021199 | HW-021199 | Phase 2 Clinical | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc, Humanwell Puracap (Likang) Pharmaceuticals Co Ltd | Idiopathic Pulmonary Fibrosis | Details |
| HNC664 | HNC664; HNC-664 | Phase 1 Clinical | Guangzhou Henovcom Bioscience Co Ltd | Idiopathic Pulmonary Fibrosis; Pancreatic Neoplasms | Details |
| Cudetaxestat | PAT-409; BLD-0409 | Phase 1 Clinical | Blade Therapeutics Inc | Idiopathic Pulmonary Fibrosis; Liver Diseases; Metabolic Dysfunction-Associated Steatotic Liver Disease | Details |
| NXC-680 | NXC-680 | Phase 1 Clinical | Nextgen Bioscience Inc | Idiopathic Pulmonary Fibrosis | Details |
| HNC-1058 | HNC-1058 | Phase 1 Clinical | Guangzhou Henovcom Bioscience Co Ltd | Idiopathic Pulmonary Fibrosis | Details |
| FTP-198 | FTP-198 | Phase 1 Clinical | Haisco Pharmaceutical Group Co Ltd | Idiopathic Pulmonary Fibrosis | Details |
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