EMMPRIN

EMMPRIN Molekülinformation

Englischer Name	Basigin	Anzahl der inverkehr gebrachten Arzneimittel	1
Anzahl der klinischen Arzneimittel	4	Target-Alias	BSG，Extracellular matrix metalloproteinase inducer，UNQ6505/PRO21383，Basigin (Ok Blood Group)，Tumor Cell-Derived Collagenase Stimulatory Factor，Leukocyte Activation Antigen M6，Collagenase Stimulatory Factor，Basigin，5F7，Ok Blood Group，CD147 Antigen，EMPRIN，CD147，OK，TCSF，EMMPRIN，SLC7A11，OK blood group antigen
Höchste Forschungs- und Entwicklungsphase	Approved

Englischer Name	Basigin
Target-Alias	BSG，Extracellular matrix metalloproteinase inducer，UNQ6505/PRO21383，Basigin (Ok Blood Group)，Tumor Cell-Derived Collagenase Stimulatory Factor，Leukocyte Activation Antigen M6，Collagenase Stimulatory Factor，Basigin，5F7，Ok Blood Group，CD147 Antigen，EMPRIN，CD147，OK，TCSF，EMMPRIN，SLC7A11，OK blood group antigen
Anzahl der inverkehr gebrachten Arzneimittel	1
Anzahl der klinischen Arzneimittel	4
Höchste Forschungs- und Entwicklungsphase	Approved

EMMPRIN Produktliste

Attribut
Protein (6)
Produktbibliothek
Online (6)
Spezies
Human (4)Mouse (1)Cynomolgus (1)
Etikett
His Tag (3)Fc Tag (1)His Tag & Avi Tag (2)
Marker
Unconjugated (3)Biotin-labeled (2)FITC Labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT CD7-H5222	Human	HEK293	Human EMMPRIN / CD147 Protein, His Tag (MALS verified)	In den Warenkorb legen
HOT CD7-H82E0	Human	HEK293	Biotinylated Human EMMPRIN / CD147 Protein, Avitag™,His Tag (MALS verified)	In den Warenkorb legen
HOT CD7-M82E8	Mouse	HEK293	Biotinylated Mouse EMMPRIN / CD147 Protein, His,Avitag™ (MALS verified)	In den Warenkorb legen
CD7-H5259	Human	HEK293	Human EMMPRIN / CD147 Protein, Fc Tag	In den Warenkorb legen
CD7-HF222	Human	HEK293	FITC-Labeled Human EMMPRIN / CD147 Protein, His Tag	In den Warenkorb legen
CD7-C52H8	Cynomolgus	HEK293	Cynomolgus EMMPRIN / CD147 Protein, His Tag (MALS verified)	In den Warenkorb legen

Gesamtmenge6

EMMPRIN Molekülhintergrund

CD147, also known as Basigin (BSG), or extracellular matrix metalloproteinase inducer (EMMPRIN). The human basigin protein contains 269 amino acids that form two heavily glycosylated C2 type immunoglobulin-like domains at the N-terminal extracellular portion. A second form of basigin has also been characterized that contains one additional immunoglobulin-like domain in its extracellular portion. As members of the immunoglobulin superfamily play fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development, basigin is thought also to play a role in intercellular recognition and regulate several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. Basigin is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins.

EMMPRIN Molekülalias

Basigin,BSG,5F7,CD147,EMMPRIN,M6,OK,TCSF

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Mertuzumab		Phase 3 Clinical	Institute Of Medicine Fourth Military Medical University, Jiangsu Pacific Minok Biopharmaceutical Co., Ltd.	Carcinoma, Non-Small-Cell Lung; Coronavirus Disease 2019 (COVID-19)	Details
Meplazumab	HI6H8	Phase 3 Clinical	Institute Of Medicine Fourth Military Medical University, Jiangsu Pacific Minok Biopharmaceutical Co., Ltd.	Coronavirus Disease 2019 (COVID-19); Malaria; Malaria, Falciparum; Post-Acute COVID-19 Syndrome	Details
humanized ADCC cHAb18 antibody (Pacific Meinuoke/Fourth Military Medical University)		Phase 1 Clinical	Air Force Medical University	Carcinoma, Non-Small-Cell Lung	Details
CD147-CAR T cell therapy (Peking University People's Hospital)		Phase 1 Clinical	Peking University People'S Hospital	Lymphoma, T-Cell	Details

Inverkehr gebrachte Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Frühestes Markenname	Frühestes Genehmigungsland	Früheste Indikation	Früheste Genehmigungsgesellschaft	Früheste Genehmigungsdatum	Indikationen	Klinische Studie
Iodine[131I] Metuximab		Approved	Chengdu Huasun Biotechnology Co Ltd	Licartin, 利卡汀	Mainland China	Carcinoma, Hepatocellular	Chengdu Huasun Biotechnology Co Ltd	2006-10-12	Carcinoma, Hepatocellular	Details