DLL1

DLL1 Molekülinformation

Englischer NameDelta Like Canonical Notch Ligand 1Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel0Target-AliasDelta Like Canonical Notch Ligand 1,Drosophila Delta Homolog 1,Delta-Like Protein 1,H-Delta-1,Epididymis Secretory Sperm Binding Protein,Delta (Drosophila)-Like 1,Delta-Like 1 (Drosophila),DELTA1,NEDBAS,Delta1,Delta,DL1,Drosophila Delta homolog 1 (Delta1; H-Delta-1)
Höchste Forschungs- und EntwicklungsphasePreclinical
Englischer NameDelta Like Canonical Notch Ligand 1
Target-AliasDelta Like Canonical Notch Ligand 1,Drosophila Delta Homolog 1,Delta-Like Protein 1,H-Delta-1,Epididymis Secretory Sperm Binding Protein,Delta (Drosophila)-Like 1,Delta-Like 1 (Drosophila),DELTA1,NEDBAS,Delta1,Delta,DL1,Drosophila Delta homolog 1 (Delta1; H-Delta-1)
Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel0
Höchste Forschungs- und EntwicklungsphasePreclinical

DLL1 Produktliste

  • Attribut

    Protein (3)Cell Grade Beads (2)

  • Produktbibliothek

    Online (5)

  • Spezies

    Human (3)- (2)

  • Etikett

    His Tag (1)His Tag & Avi Tag (1)- (2)Fc Tag (1)

  • Marker

    Unconjugated (2)Biotin-labeled (1)- (2)

DLL1 Molekülhintergrund

Delta-like protein 1 (DLL1) is also known as Drosophila Delta homolog 1 (Delta1 or H-Delta-1), which contains one DSL domain and eight EGF-like domains. DLL1 is ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. As for expression, DLL1 is expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney. Furthermore, DLL1 acts as a ligand for Notch receptors. Also, DLL1 can block the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.

DLL1 Molekülalias

DLL1,Delta1,H-Delta-1
  • Molekülinformation
  • Produktliste