CXCR5 Overview
Molecule Name
C-X-C motif chemokine receptor 5
Synonyms
BLR1, CD185, MDR15
Drug Development Progress
Drugs in Clinical Trials2
Approved Drugs0
Highest Development StagePhase 2 Clinical
Target Synonym
Burkitt Lymphoma Receptor 1， GTP-Binding Protein，C-X-C Motif Chemokine Receptor 5，Burkitt Lymphoma Receptor 1， GTP Binding Protein (Chemokine (C-X-C Motif) Receptor 5)，Chemokine (C-X-C Motif) Receptor 5，Monocyte-Derived Receptor 15，MDR-15，C-X-C Chemokine Receptor Type 5，Burkitt Lymphoma Receptor 1，CD185 Antigen，CXCR-5，CD185，MDR15，BLR1，CXCR5，CXC-R5，Receptors， CXCR5
Background
Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.
CXCR5 Product List
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Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| PF-06835375 | PF-06835375 | Phase 2 Clinical | Pfizer Inc | Arthritis, Rheumatoid; Lupus Erythematosus, Systemic; Lupus Vulgaris; Purpura, Thrombocytopenic, Idiopathic | Details |
| CXCR5 Modified EGFR Chimeric Antigen Receptor Autologous T Cell Therapy | Phase 1 Clinical | Second Affiliated Hospital Of Guangzhou Medical University | Carcinoma, Non-Small-Cell Lung | Details |