CXCL1

CXCL1 Produktliste

Attribut
Protein (1)
Produktbibliothek
Online (1)
Spezies
Human (1)
Etikett
Fc Tag (1)
Marker
Unconjugated (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
CX1-H5253	Human	HEK293	Human CXCL1 Protein, Fc Tag (MALS verified)				In den Warenkorb legen

Gesamtmenge1

CXCL1 Molekülhintergrund

Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small molecule of cytokines belonging to the CXC chemokine family. Also known as growth-regulated oncogene alpha (Growth-regulated oncogene alpha, GROα). It's also known as keratinocytes-derived chemokine (KC) in mice or cytokine-induced neutrophil chemoattractant type-1 (CINC-1) in rats. In humans, this protein is encoded by the gene Cxcl1 and is located on human chromosome 4 among genes for other CXC chemokines. The chemokine CXCL1 is expressed by macrophages, neutrophils and epithelial cells. The chemokine CXCL1 has a chemotactic effect on neutrophils. CXCL1 binds to the chemokine receptor CXCR2 and plays a role in cell chemotaxis. Human CXCL1 is clustered on chromosome 4 adjacent to many CXC chemokine genes. Major roles of CXCL1 include neovascularization, inflammation, wound healing, and tumorigenesis

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
HS-10241	HS-10241	Phase 3 Clinical	Jiangsu Hansoh Pharmaceutical Group Co Ltd	Solid tumours; Carcinoma; Neoplasms; Carcinoma, Non-Small-Cell Lung	Details
Zanzalintinib	XL-092	Phase 3 Clinical	Exelixis Inc	Solid tumours; Leiomyosarcoma; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Neoplasms; Carcinoma, Transitional Cell; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular	Details
Refanalin	ANG-3777; BB-3; SNV-003	Phase 3 Clinical	Vifor Pharma Ag, Elicio Therapeutics	Myocardial Infarction; Pneumonia; Coronavirus Disease 2019 (COVID-19); Acute Kidney Injury; Delayed Graft Function	Details
Fosgonimeton	ATH-1017; NDX-1017	Phase 3 Clinical	M3 Biotechnology	Alzheimer Disease; Lewy Body Disease	Details
Sitravatinib	MGCD-516; IND-155305; MGCD-0516; MG-91516; MG-516	Phase 3 Clinical		Breast Neoplasms; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms; Carcinoma, Hepatocellular; Endometrial Neoplasms; Lung Neoplasms; Metastatic breast cancer; Esophageal Squamous Cell Carcinoma; Mouth Neoplasms; Carcinoma, Squamous Cell; Hepatic Insufficiency; Ureteral Neoplasms; Solid tumours; Lung Diseases; Liposarcoma; Uveal melanoma; Triple Negative Breast Neoplasms; Carcinoma, Transitional Cell; Neoplasms; Carcinoma; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Kidney Neoplasms; Biliary Tract Neoplasms	Details
HS-20117	HS-20117; PM1080; PM-1080	Phase 3 Clinical	Biotheus Inc	Solid tumours; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung	Details
Telisotuzumab adizutecan	ABBV-400	Phase 3 Clinical	Abbvie Inc	Solid tumours; Biliary Tract Neoplasms; Stomach Neoplasms; Squamous Cell Carcinoma of Head and Neck; Esophageal Neoplasms; Triple Negative Breast Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Esophageal Squamous Cell Carcinoma; Esophageal adenocarcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung	Details
SC-0011	SC-0011	Phase 3 Clinical	Shijiazhuang Zhikang Hongren New Drug Development Co Ltd	Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung	Details
AL-2846	AL-2846	Phase 3 Clinical	Advenchen Laboratories Nanjing Ltd	Neurofibromatoses; Neurilemmoma; Neurofibromatosis 1; Carcinoma, Non-Small-Cell Lung; Lung Neoplasms; Thyroid Neoplasms; Colorectal Neoplasms; Prostatic Neoplasms; Medullary thyroid cancer (MTC); Solid tumours; Neurofibroma; Ganglioglioma; Neoplasms; Pancreatic Neoplasms; Stomach Neoplasms; Liver Neoplasms; Ovarian Neoplasms; Bone metastases	Details
Ningetinib Tosylate	CT-053-PTSA; CT-053	Phase 2 Clinical	Hec Pharm Co Ltd	Intestinal Neoplasms; Solid tumours; Carcinoma, Renal Cell; Stomach Neoplasms; Leukemia, Myeloid, Acute; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung	Details
Pamvatamig	MCLA-129	Phase 2 Clinical	Merus Nv	Solid tumours; Head and Neck Neoplasms; Stomach Neoplasms; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Esophageal Squamous Cell Carcinoma; Carcinoma, Non-Small-Cell Lung	Details
Merestinib	5OGS5K699E; LY-2801653	Phase 2 Clinical	Eli Lilly And Company	Biliary Tract Neoplasms; Skin Melanoma; Bone metastases; Solid tumours; Neoplasms; Pancreatic Neoplasms; Microsatellite instability-high cancer; Lymphoma, Mantle-Cell; Breast Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Gallbladder Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung	Details
Sym-015	Sym-015	Phase 2 Clinical	Symphogen A/S	Neoplasms; Carcinoma, Non-Small-Cell Lung	Details
ABN-401	ABN-401; KDDF-201603-08	Phase 2 Clinical	Abion Inc	Solid tumours; Neoplasms	Details
REGN-5093-M114	METxMET-M114; REGN5093-M114	Phase 2 Clinical		Carcinoma, Non-Small-Cell Lung	Details
Glesatinib	MGCD-265; MG-90265X; 7Q29OXD98N; MG-90265H9; MG-90265gly; MG-90265	Phase 2 Clinical		Neoplasms; Carcinoma, Non-Small-Cell Lung	Details
Bafisontamab	FIT-013a; EMB-01	Phase 2 Clinical	Shanghai Epimab Biotherapeutics, Inc	Biliary Tract Neoplasms; Liver Neoplasms; Carcinoid Tumor; Stomach Neoplasms; Neoplasms; Digestive System Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Neoplasm Metastasis; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular	Details
GB-263	GB-263; GB-263T	Phase 2 Clinical	Genor Biopharma Co Ltd	Solid tumours; Neoplasms; Carcinoma, Non-Small-Cell Lung	Details
Elzovantinib	TPX-0022	Phase 2 Clinical	Turning Point Therapeutics Inc	Solid tumours; Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis	Details
PRO-1286	PRO-1286; GEN1286; GEN-1286	Phase 2 Clinical	ProfoundBio (Suzhou) Co Ltd	Solid tumours; Neoplasms	Details
Do-1	Do-1	Phase 2 Clinical	DeuterOncology NV	Lung Neoplasms	Details
EMI-137	EMI-137; GE-137	Phase 2 Clinical	Ge Healthcare	Esophageal Neoplasms; Extranodal Extension; Colonic Neoplasms; Barrett Esophagus	Details
Davutamig	REGN-5093	Phase 2 Clinical		Carcinoma, Non-Small-Cell Lung	Details
CKD-702		Phase 2 Clinical	Chong Kun Dang Pharmaceutical Corp	Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung	Details
Recombinant adenovirus-hepatocyte growth factor(Institute Of Radiation And Radiation Medicine, Chinese Academy Of Military Medical Sciences)		Phase 2 Clinical	Institute Of Radiation And Radiation Medicine, Chinese Academy Of Military Medical Sciences, Beijing Haitai United Pharmaceutical Technology Development Co Ltd	Myocardial Ischemia	Details
RC-108	RC-108; RC108	Phase 2 Clinical	RemeGen Co Ltd	Solid tumours; Digestive System Neoplasms; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung	Details
Emibetuzumab	LA-480; LY-2875358	Phase 2 Clinical	Eli Lilly And Company	Solid tumours; Carcinoma, Renal Cell; Esophageal Neoplasms; Stomach Neoplasms; Neoplasms; Lymphoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular	Details
SHR-A1403	SHR-A1403	Phase 1 Clinical		Solid tumours	Details
CM-118	CM-118	Phase 1 Clinical	Xcovery	Neoplasms; Carcinoma, Non-Small-Cell Lung	Details
Kanitinib	CX-1003	Phase 1 Clinical	Beijing Konruns Pharmaceutical Co Ltd, Guangzhou Yingsheng Bio Technology Co Ltd	Solid tumours	Details
BPI-9016	BPI-9016; BPI-9016M	Phase 1 Clinical	Betta Pharmaceuticals Co Ltd	Solid tumours; Carcinoma, Non-Small-Cell Lung	Details
HLX-55	HLX-55; KTN-0216	Phase 1 Clinical	Kolltan Pharmaceuticals Inc	Solid tumours	Details
Pamufetinib	TAS-115	Phase 1 Clinical	Taiho Pharmaceutical Co Ltd, Otsuka Pharmaceutical Co Ltd	Neoplasms	Details
Boxitinib Hydrochloride		Phase 1 Clinical	Hec Pharm Co Ltd	Stomach Neoplasms; Carcinoma, Renal Cell; Breast Neoplasms; Glioma; Lung Neoplasms	Details
BYON-3521	BYON-3521	Phase 1 Clinical	Byondis Bv	Solid tumours; Neoplasms	Details
ATH-1020	ATH-1020	Phase 1 Clinical	Athira Pharma Inc		Details
QBH-196	QBH-196	Phase 1 Clinical	Shenyang Pharmaceutical University	Solid tumours; Stomach Neoplasms	Details
BG-T187	BG-T187; BGT187	Phase 1 Clinical		Solid tumours; Lung Neoplasms; Gastrointestinal Neoplasms	Details
[11C]savolitinib	[11C]savolitinib	Phase 1 Clinical	Astrazeneca Plc		Details
[14C]HS-10241	[14C]HS-10241	Phase 1 Clinical	Jiangsu Hansoh Pharmaceutical Group Co Ltd	Carcinoma, Non-Small-Cell Lung	Details
ABBV-303	ABBV-303; DF-4101	Phase 1 Clinical	Dragonfly Therapeutics Llc	Solid tumours	Details
FPI-2107	[111In]-FPI-2107	Phase 1 Clinical		Solid tumours; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung	Details
FPI-2053	FPI-2053	Phase 1 Clinical	Astrazeneca Plc	Solid tumours; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung	Details
DM-005	DM-005; DM005	Phase 1 Clinical	Doma Biopharmaceutical (Suzhou) Co Ltd	Solid tumours; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Non-Small-Cell Lung	Details
ANS-014004	ANS014004; ANS-014004; ANS-01; ANS01	Phase 1 Clinical		Solid tumours; Neoplasms	Details
FPI-2068	[225Ac]-FPI-2068; FPI-2068	Phase 1 Clinical	Astrazeneca Plc	Solid tumours; Squamous Cell Carcinoma of Head and Neck; Neoplasms; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung	Details
SPH-3348	SPH-3348; SPH3348; I-020	Phase 1 Clinical	Shanghai Pharmaceuticals Holding Co Ltd	Solid tumours; Neoplasms	Details
MYTX-011	MYTX-011	Phase 1 Clinical	Mythic Therapeutics Inc	Carcinoma, Non-Small-Cell Lung	Details
AZD9592	AZD-9592; AZD9592	Phase 1 Clinical	Astrazeneca Plc	Solid tumours; Head and Neck Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung	Details
TAVO-412	TAVO-412	Phase 1 Clinical	Tavotek Biotherapeutics (Hong Kong) Ltd, Tuochuang Biotechnology (Jiangsu) Co Ltd	Solid tumours; Neoplasms	Details
NP-107	NP107; NP-107	Phase 1 Clinical	Shanghai Nawei Biotechnology Co Ltd	Solid tumours	Details
ASKC-202	ASKC202	Phase 1 Clinical	Jiangsu Aosaikang Pharmaceutical Co Ltd	Solid tumours; Carcinoma, Non-Small-Cell Lung	Details
LMV-12(HE003)	LMV-12(HE003)	Phase 1 Clinical	Nanchang Hongyi Technology Co Ltd	Solid tumours	Details
GST-HG161	GST-HG161	Phase 1 Clinical	Fujian Cosunter Pharmaceutical Co Ltd	Solid tumours; Neoplasms; Carcinoma, Hepatocellular	Details
Metatinib Trometamol	BMS-817378; SIM-817378	Phase 1 Clinical	Bristol-Myers Squibb Company	Solid tumours; Liver Neoplasms; Stomach Neoplasms; Colorectal Neoplasms	Details
NP-01 (Shijiazhuang No.4 Pharmaceutical/Nanjing Nadingfei Medical Technology)	NP-01	Phase 1 Clinical	Shijiazhuang No 4 Pharmaceutical Co Ltd, Nanjing Nadingfei Pharmaceutical Technology Co Ltd	Solid tumours; Liver Neoplasms; Stomach Neoplasms; Lung Neoplasms	Details
SAIT-301	SAIT-301	Phase 1 Clinical	Samsung Medical Center	Neoplasms	Details
NPS-1034	HOPE-777; KDDF-201111-02		Neopharma Ltd		Details

Inverkehr gebrachte Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Frühestes Markenname	Frühestes Genehmigungsland	Früheste Indikation	Früheste Genehmigungsgesellschaft	Früheste Genehmigungsdatum	Indikationen	Klinische Studie
Crizotinib	PF-1066; PF-2341066; PF-02341066; PF-002341066	Approved	Pfizer Inc	赛可瑞, Xalkori	United States	Carcinoma, Non-Small-Cell Lung	Pf Prism Cv	2011-08-26	Urethral Neoplasms; Neoplasm Metastasis; Adenocarcinoma; Neurilemmoma; Carcinoma, Non-Small-Cell Lung; Lung Neoplasms; Granuloma, Plasma Cell; Endometrial Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma; Ureteral Neoplasms; Solid tumours; Lymphoma, Primary Cutaneous Anaplastic Large Cell; Neuroblastoma; Urinary Bladder Neoplasms; Myofibroma; Uveal melanoma; Multiple Myeloma; Neurofibromatosis 2; Neoplasms; Renal Insufficiency; Hematologic Neoplasms	Details
Unecritinib	TQ-B3101; TTQ-B3101	Approved	Southeast University	安柏尼	Mainland China	Carcinoma, Non-Small-Cell Lung	Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd	2024-04-24	Stomach Neoplasms; Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma; Carcinoma, Non-Small-Cell Lung	Details
Glumetinib	HH-SCC244; SCC244; SCC-244	Approved	Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences, Shanghai Greenvalley Pharmaceutical Co Ltd	海益坦	Mainland China	Carcinoma, Non-Small-Cell Lung	ShangHai HaiHe Biopharma Co Ltd	2023-03-07	Solid tumours; Carcinoma, Non-Small-Cell Lung	Details
Tepotinib hydrochloride hydrate	MSC-2156119J; MSC-2156119; EMD-1214063	Approved	Merck Serono	Tepmetko, テプミトコ, TEPMETKO	Japan	Carcinoma, Non-Small-Cell Lung	Merck KGaA, Darmstadt, Germany	2020-03-25	Solid tumours; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular	Details
Capmatinib Hydrochloride	INCB-28060; C2A374O70X; INC-280; INCB-028060; NVP-INC280-NX	Approved	Incyte Corp, Novartis Pharma Ag	Tabrecta	United States	Carcinoma, Non-Small-Cell Lung	Novartis Pharmaceuticals Corp	2020-05-06	Adenocarcinoma of Lung; Neoplasm Metastasis; Carcinoma, Hepatocellular; Melanoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Gliosarcoma; Colorectal Neoplasms; Sarcoma; Solid tumours; Neoplasms; Triple Negative Breast Neoplasms; Glioblastoma; Carcinoma; Carcinoma, Renal Cell; Kidney Neoplasms; Liver Neoplasms	Details
Savolitinib	HM-5016504; AZD-6094; HMP-504; HMPL-504	Approved	Hutchison Medipharma Ltd	沃瑞沙, ORPATHYS	Mainland China	Carcinoma, Non-Small-Cell Lung	Hutchison Medipharma Ltd	2021-06-22	Central Nervous System Neoplasms; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Lung Neoplasms; Neoplasms, Neuroepithelial; Glioma; Carcinoma, Squamous Cell; Urologic Neoplasms; Diffuse Intrinsic Pontine Glioma; Colorectal Neoplasms; Peritoneal Neoplasms; Cholangiocarcinoma; Medulloblastoma; Kidney Diseases; Colonic Neoplasms; Neoplasms; Carcinoma; Stomach Neoplasms; Esophageal Neoplasms; Rectal Neoplasms; Carcinoma, Renal Cell; Kidney Neoplasms; Solid tumours	Details
Ensartinib Hydrochloride	X-396	Approved	Xcovery	贝美纳	Mainland China	Carcinoma, Non-Small-Cell Lung	Betta Pharmaceuticals Co Ltd	2020-11-17	Sarcoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Xanthogranuloma, Juvenile; Neuroectodermal Tumors, Primitive, Peripheral; Neoplasms, Germ Cell and Embryonal; Neoplasms, Neuroepithelial; Brain metastases; Carcinoma, Squamous Cell; Glioma; Lymphoma, Non-Hodgkin; Lung Neoplasms; Histiocytic Sarcoma; Neuroblastoma; Solid tumours; Histiocytosis, Langerhans-Cell; Osteosarcoma; Sarcoma, Ewing; Central Nervous System Neoplasms; Neoplasms; Small Cell Lung Carcinoma; Wilms Tumor; Rhabdoid Tumor; Hepatoblastoma; Medulloblastoma; Ependymoma; Rhabdomyosarcoma	Details
Amivantamab	JNJ-61186372; JNJ-372; JNJ-6372; CNTO4424; CNTO-4424	Approved	Genmab A/S, Johnson & Johnson Innovative Medicine	RYBREVANT	United States	Carcinoma, Non-Small-Cell Lung	Janssen Biotech Inc	2021-05-21	Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Glioblastoma; Carcinoma, Adenoid Cystic; Colorectal Neoplasms; Glioma; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Carcinoma, Hepatocellular	Details
Cabozantinib S-malate	XL-184; BMS-907351; RO7047650; RO-7047650	Approved	Exelixis Inc	Cometriq, Cabometyx	United States	Thyroid Neoplasms; Carcinoma, Neuroendocrine	Exelixis Inc	2012-11-29	Neuroblastoma; Thyroid Neoplasms; Hepatic Insufficiency; Astrocytoma; Peritoneal Neoplasms; Bile Duct Neoplasms; Colorectal Neoplasms; Gliosarcoma; Urethral Neoplasms; Sarcoma, Clear Cell; Uterine Neoplasms; Cholangiocarcinoma; Neurofibroma, Plexiform; Brain Neoplasms; Adenocarcinoma, Clear Cell; Carcinoma, Adenosquamous; Medullary thyroid cancer (MTC); Sarcoma, Ewing; Sarcoma; Osteosarcoma; Sarcoma, Alveolar Soft Part; Neoplasm Metastasis; Melanoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Endometrioid; Thyroid Cancer, Papillary; Meningioma; Paraganglioma; Neoplasms, Germ Cell and Embryonal; Carcinoma, Hepatocellular; Prostatic Neoplasms; Glioma; Brain metastases; Endometrial Neoplasms; Leukemia, Myeloid, Acute; Carcinoma, Squamous Cell; Lymphoma; Carcinoma, Neuroendocrine; Fallopian Tube Neoplasms; Carcinoma, Renal Cell; Adenoma, Islet Cell; Glioblastoma; Carcinoma, Ovarian Epithelial; Renal Insufficiency; Hepatoblastoma; Pheochromocytoma; Carcinoid Tumor; Carcinoma, Merkel Cell; Rejection of liver transp	Details
Vebreltinib	PLB-1001; CBT-101; APL-101; CBI-3103	Approved	Crown Bioscience Inc		Mainland China	Carcinoma, Non-Small-Cell Lung	Beijing Purunao Biotechnology Co Ltd	2023-11-16	Colonic Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Glioma; Thyroid Neoplasms; Lung Neoplasms; Hepatic Insufficiency; Astrocytoma; Brain Neoplasms; Solid tumours; Glioblastoma; Pancreatic Neoplasms; Ganglioglioma; Neoplasms; Carcinoma, Renal Cell; Stomach Neoplasms; Esophageal Neoplasms; Kidney Neoplasms	Details