CX3CL1

CX3CL1 Molekülinformation

Englischer Name	C-X3-C motif chemokine ligand 1	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1	Target-Alias	Small Inducible Cytokine Subfamily D (Cys-X3-Cys)， Member 1 (Fractalkine， Neurotactin)，Small Inducible Cytokine Subfamily D (Cys-X3-Cys)， Member-1，CX3CL1，Small-inducible cytokine D1，FKN，Fractalkine，A-152E5.2，C-X3-C Motif Chemokine Ligand 1，Chemokine (C-X3-C Motif) Ligand 1，CX3C Membrane-Anchored Chemokine，C-X3-C Motif Chemokine 1，Neurotactin，SCYD1，NTT，C3Xkine，ABCD-3，CXC3C，CXC3，NTN，Chemokine CX3CL1
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Englischer Name	C-X3-C motif chemokine ligand 1
Target-Alias	Small Inducible Cytokine Subfamily D (Cys-X3-Cys)， Member 1 (Fractalkine， Neurotactin)，Small Inducible Cytokine Subfamily D (Cys-X3-Cys)， Member-1，CX3CL1，Small-inducible cytokine D1，FKN，Fractalkine，A-152E5.2，C-X3-C Motif Chemokine Ligand 1，Chemokine (C-X3-C Motif) Ligand 1，CX3C Membrane-Anchored Chemokine，C-X3-C Motif Chemokine 1，Neurotactin，SCYD1，NTT，C3Xkine，ABCD-3，CXC3C，CXC3，NTN，Chemokine CX3CL1
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

CX3CL1 Produktliste

Attribut
Protein (4)
Produktbibliothek
Online (4)
Spezies
Human (3)Cynomolgus (1)
Etikett
His Tag (3)His Tag & Avi Tag (1)
Marker
Biotin-labeled (2)Unconjugated (2)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT CX1-H8221	Human	HEK293	Biotinylated Human CX3CL1 Protein, His Tag, ultra sensitivity (primary amine labeling)	In den Warenkorb legen
CX1-H5221	Human	HEK293	Human CX3CL1 / Fractalkine Protein, His Tag	In den Warenkorb legen
CX1-H82E6	Human	HEK293	Biotinylated Human CX3CL1 Protein, His,Avitag™	In den Warenkorb legen
CX1-C5222	Cynomolgus	HEK293	Cynomolgus CX3CL1 / Fractalkine Protein, His Tag (MALS verified)	In den Warenkorb legen

Gesamtmenge4

CX3CL1 Molekülhintergrund

Fractalkine is also known as C-X3-C motif chemokine 1 (CX3CL1) and neurotactin. Fractalkine is a large cytokine protein of 373 amino acids, it contains multiple domains and is the only known member of the CX3C chemokine family. Fractalkine is found commonly throughout the brain, particularly in neural cells, and its receptor is known to be present on microglial cells. It has also been found to be essential for microglial cell migration. CX3CL1 is also up-regulated in the hippocampus during a brief temporal window following spatial learning, the purpose of which may be to regulate glutamate-mediated neurotransmission tone. This indicates a possible role for the chemokine in the protective plasticity process of synaptic scaling.