Clusterin

Clusterin Molekülinformation

Englischer Name	Clusterin	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1	Target-Alias	Epididymis Secretory Sperm Binding Protein，CLI，Apolipoprotein J，ApoJbeta，Complement cytolysis inhibitor a chain，Testosterone-repressed prostate message 2，Complement cytolysis inhibitor b chain，ApoJalpha，AAG4，Complement cytolysis inhibitor，NA1/NA2，APOJ，CLU，Clusterin，Complement-Associated Protein SP-40，40，Complement Lysis Inhibitor，Sulfated Glycoprotein 2，Ku70-Binding Protein 1，TRPM-2，KUB1，Clusterin (Complement Lysis Inhibitor， SP-40，40， Sulfated Glycoprotein 2， Testosterone-Repressed Prostate Message 2， Apolipoprotein J)，Aging-Associated Gene 4 Protein，Aging-Associated Protein 4，APO-J，SGP-2，SP-40，CLU1，CLU2，SGP2，TRPM2
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Englischer Name	Clusterin
Target-Alias	Epididymis Secretory Sperm Binding Protein，CLI，Apolipoprotein J，ApoJbeta，Complement cytolysis inhibitor a chain，Testosterone-repressed prostate message 2，Complement cytolysis inhibitor b chain，ApoJalpha，AAG4，Complement cytolysis inhibitor，NA1/NA2，APOJ，CLU，Clusterin，Complement-Associated Protein SP-40，40，Complement Lysis Inhibitor，Sulfated Glycoprotein 2，Ku70-Binding Protein 1，TRPM-2，KUB1，Clusterin (Complement Lysis Inhibitor， SP-40，40， Sulfated Glycoprotein 2， Testosterone-Repressed Prostate Message 2， Apolipoprotein J)，Aging-Associated Gene 4 Protein，Aging-Associated Protein 4，APO-J，SGP-2，SP-40，CLU1，CLU2，SGP2，TRPM2
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Clusterin Produktliste

Attribut
Protein (2)
Produktbibliothek
Online (2)
Spezies
Human (1)Hamster (1)
Etikett
His Tag (2)
Marker
Unconjugated (2)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
CLU-H5227	Human	HEK293	Human Clusterin / CLUS Protein, His Tag				In den Warenkorb legen
CLU-H53H3	Hamster	CHO	Hamster Clusterin / CLUS Protein, His Tag				In den Warenkorb legen

Gesamtmenge2

Produktanfrage

Clusterin Molekülhintergrund

Clusterin (CLU/ApoJ) is a sticky, CHO-derived glycoprotein secreted as a ~75–80 kDa disulfide-linked heterodimer. Due to hydrophobic/glycan-mediated interactions, it often co-purifies with mAbs and persists through Protein A, posing risks to product stability. As a high-priority HCP, residual CLU requires targeted monitoring via orthogonal methods (LC-MS/MS or specific ELISA) alongside total HCP assays.

Clusterin Molekülalias

CLU,Clusterin,AAG4,APOJ,CLI,KUB1,SGP-2,SP-40,TRPM2

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Sotevtamab	AB-sCLU mAB; 16B5; AB-16B5	Phase 2 Clinical	National Research Council Biotechnology Research Institute	Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Neoplasm Metastasis; Solid tumours	Details