CEACAM-1

CEACAM-1 Molekülinformation

Englischer NameCarcinoembryonic antigen related cell adhesion molecule 1Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel1Target-AliasCEACAM1,Biliary glycoprotein 1,BGP,CD66a,Carcinoembryonic Antigen Related Cell Adhesion Molecule 1,CD66a Antigen,BGP1,Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1,Antigen CD66,BGP-1,BGPI,CEA Cell Adhesion Molecule 1,Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein)
Höchste Forschungs- und EntwicklungsphasePhase 2 Clinical
Englischer NameCarcinoembryonic antigen related cell adhesion molecule 1
Target-AliasCEACAM1,Biliary glycoprotein 1,BGP,CD66a,Carcinoembryonic Antigen Related Cell Adhesion Molecule 1,CD66a Antigen,BGP1,Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1,Antigen CD66,BGP-1,BGPI,CEA Cell Adhesion Molecule 1,Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein)
Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel1
Höchste Forschungs- und EntwicklungsphasePhase 2 Clinical

CEACAM-1 Produktliste

  • Attribut

    Protein (3)

  • Produktbibliothek

    Online (3)

  • Spezies

    Human (2)Cynomolgus (1)

  • Etikett

    His Tag (2)His Tag & Avi Tag (1)

  • Marker

    Unconjugated (2)Biotin-labeled (1)

CEACAM-1 Molekülhintergrund

Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is also known as Biliary glycoprotein 1 (BGP1), CD66a, which belongs to the immunoglobulin superfamily or CEA family. CEACAM1 /CD66a contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CEACAM1 /CD66a was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 / BGP-1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.

CEACAM-1 Molekülalias

CEACAM1,CD66a,BGP,BGP1,BGPI

Klinische Arzneimittelinformation

Englischer NameForschungscodeForschungsphaseFirmaIndikationenKlinische Studie
CM-24CM-24 (MK-6018); MK-6018; CM-24Phase 2 ClinicalMerck Sharp & Dohme CorpCarcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Melanoma; Ovarian Neoplasms; Pancreatic Neoplasms; Solid tumours; Stomach Neoplasms; Thyroid Cancer, Papillary; Urinary Bladder Neoplasms
Details
  • Molekülinformation
  • Produktliste
  • Klinische Arzneimittelinformation