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CEACAM-1

CEACAM-1 Overview

English Name	Carcinoembryonic antigen related cell adhesion molecule 1	Approved Drugs	0
Drugs in Clinical Trials	1	Target Synonym	CEACAM1，Biliary glycoprotein 1，BGP，CD66a，Carcinoembryonic Antigen Related Cell Adhesion Molecule 1，CD66a Antigen，BGP1，Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1，Antigen CD66，BGP-1，BGPI，CEA Cell Adhesion Molecule 1，Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein)
Highest Development Stage	Phase 2 Clinical

English Name	Carcinoembryonic antigen related cell adhesion molecule 1
Target Synonym	CEACAM1，Biliary glycoprotein 1，BGP，CD66a，Carcinoembryonic Antigen Related Cell Adhesion Molecule 1，CD66a Antigen，BGP1，Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1，Antigen CD66，BGP-1，BGPI，CEA Cell Adhesion Molecule 1，Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein)
Approved Drugs	0
Drugs in Clinical Trials	1
Highest Development Stage	Phase 2 Clinical

CEACAM-1 Product List

Product Category
Protein (3)
Product Status
Launched (3)
Species
Human (2)Cynomolgus (1)
Tag
His Tag (2)His Tag & Avi Tag (1)
Conjugate
Unconjugated (2)Biotin-labeled (1)

Cat. No.	Species	Host	Product Description
CE1-H5220	Human	HEK293	Human CEACAM-1 / CD66a Protein, His Tag, low endotoxin
CE1-H82E5	Human	HEK293	Biotinylated Human CEACAM-1 / CD66a Protein, Avitag™,His Tag
CE1-C52H6	Cynomolgus	HEK293	Cynomolgus CEACAM-1 / CD66a Protein, His Tag

Total: 3

CEACAM-1 Background

Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is also known as Biliary glycoprotein 1 (BGP1), CD66a, which belongs to the immunoglobulin superfamily or CEA family. CEACAM1 /CD66a contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CEACAM1 /CD66a was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 / BGP-1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.

CEACAM-1 Synonyms

CEACAM1,CD66a,BGP,BGP1,BGPI

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
CM-24	CM-24 (MK-6018); MK-6018; CM-24	Phase 2 Clinical	Merck Sharp & Dohme Corp	Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Melanoma; Ovarian Neoplasms; Pancreatic Neoplasms; Solid tumours; Stomach Neoplasms; Thyroid Cancer, Papillary; Urinary Bladder Neoplasms	Details