CD58

CD58 Molekülinformation

Englischer Name	Lymphocyte function-associated antigen 3	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1	Target-Alias	CD58 Antigens，Surface glycoprotein LFA-3，LFA3，LFA-3，CD58 Molecule，CD58 Antigen，CD58，CD58 Antigen， (Lymphocyte Function-Associated Antigen 3)
Höchste Forschungs- und Entwicklungsphase	Clinical

Englischer Name	Lymphocyte function-associated antigen 3
Target-Alias	CD58 Antigens，Surface glycoprotein LFA-3，LFA3，LFA-3，CD58 Molecule，CD58 Antigen，CD58，CD58 Antigen， (Lymphocyte Function-Associated Antigen 3)
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1
Höchste Forschungs- und Entwicklungsphase	Clinical

CD58 Produktliste

Attribut
Protein (2)
Produktbibliothek
Online (2)
Spezies
Human (2)
Etikett
His Tag (1)Fc Tag (1)
Marker
Unconjugated (2)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
LF3-H5225	Human	HEK293	Human CD58 / LFA-3 Protein, His Tag				In den Warenkorb legen
LF3-H5256	Human	HEK293	Human CD58 / LFA-3 Protein, Fc Tag				In den Warenkorb legen

Gesamtmenge2

CD58 Molekülhintergrund

CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.