CD44

CD44 Molekülinformation

Englischer Name	CD44 antigen	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	10	Target-Alias	Hermes Antigen，Hyaluronate Receptor，Cell Surface Glycoprotein CD44，MC56，PGP-1，CD44，CDW44，GP90 Lymphocyte Homing/Adhesion Receptor，MIC4，LHR，Hematopoietic Cell E- And L-Selectin Ligand，CD44 Antigen (Homing Function And Indian Blood Group System)，MDU3，Extracellular Matrix Receptor III，Heparan Sulfate Proteoglycan，HUTCH-I，ECMR-III，Epican，Chondroitin Sulfate Proteoglycan 8，Soluble CD44，MDU2，Pgp1，CSPG8，HCELL，Phagocytic Glycoprotein 1，Indian Blood Group Antigen，IN，Phagocytic Glycoprotein I，CD44 Molecule (Indian Blood Group)，CD44 Antigen，PGP-I，Homing Function And Indian Blood Group System，Hyaluronan Receptors，CD44R
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Englischer Name	CD44 antigen
Target-Alias	Hermes Antigen，Hyaluronate Receptor，Cell Surface Glycoprotein CD44，MC56，PGP-1，CD44，CDW44，GP90 Lymphocyte Homing/Adhesion Receptor，MIC4，LHR，Hematopoietic Cell E- And L-Selectin Ligand，CD44 Antigen (Homing Function And Indian Blood Group System)，MDU3，Extracellular Matrix Receptor III，Heparan Sulfate Proteoglycan，HUTCH-I，ECMR-III，Epican，Chondroitin Sulfate Proteoglycan 8，Soluble CD44，MDU2，Pgp1，CSPG8，HCELL，Phagocytic Glycoprotein 1，Indian Blood Group Antigen，IN，Phagocytic Glycoprotein I，CD44 Molecule (Indian Blood Group)，CD44 Antigen，PGP-I，Homing Function And Indian Blood Group System，Hyaluronan Receptors，CD44R
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	10
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

CD44 Produktliste

Attribut
Protein (2)Antibody (2)
Produktbibliothek
Online (4)
Spezies
Human (2)Rabbit (1)Mouse (1)
Etikett
His Tag (1)Fc Tag (1)- (2)
Marker
Unconjugated (3)PE Labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
CD4-H5226	Human	HEK293	Human CD44 Protein, His Tag	In den Warenkorb legen
AIDD‑Ready PG1-H5255	Human	HEK293	Human CD44 Protein, Fc Tag (HPLC verified)	In den Warenkorb legen
FABm039-01	Mouse	-	PE-Labeled Monoclonal Anti-Human CD44 Antibody, Mouse IgG1 (AS625) (0.03% Proclin)	In den Warenkorb legen
HGS-S246	Rabbit	-	Recombinant Monoclonal Anti-CD44 Antibody, Rabbit (5G3)	In den Warenkorb legen

Gesamtmenge4

Produktanfrage

CD44 Molekülhintergrund

CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. CD44 is expressed in a large number of mammalian cell types. CD44 is a receptor for hyaluronic acid and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 function is controlled by its posttranslational modifications. One critical modification involves discrete sialofucosylations rendering the selectin-binding glycoform of CD44 called HCELL (for Hematopoietic Cell E-selectin/L-selectin Ligand). CD44 participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms.

CD44 Molekülalias

CD44,CDW44,CSPG8,ECMR-III,HCELL,HUTCH-I,IN,LHR,MC56,MDU2,MDU3,MIC4,Pgp1,Epican

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Paclitaxel/Hyaluronic acid		Phase 3 Clinical	Fidia Pharma	Carcinoma, Papillary; Urinary Bladder Neoplasms	Details
CA-102N	CA-102N	Phase 2 Clinical	Holy Stone Healthcare Co Ltd	Colorectal Neoplasms; Solid tumours	Details
P-134	P-134; P134	Phase 2 Clinical	Tianjin Tasly Pharmaceutical Co Ltd	Glioblastoma	Details
Rosuvastatin liposome encapsulated therapy (Beijing Inno Medicine)	YN001; YN-001	Phase 2 Clinical	Beijing Inno Medicine Co Ltd	Atherosclerosis; Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Artery Disease; Erectile Dysfunction	Details
AMT-116(Multitude Therapeutics)	AMT-116; AMT-116-ADC	Phase 2 Clinical	Multitude Therapeutics Inc	Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Head and Neck Neoplasms; Solid tumours	Details
Hyaluronic acid/Fluorouracil	HA-5FU; HA-5-fluorouracil; Hyaluronic acid-5-fluorouracil complex; Hyaluronan acid-5-fluorouracil complex	Phase 2 Clinical	Alchemia Ltd, Monash University	Colorectal Neoplasms	Details
AMC-303	AMC-303; HP-558	Phase 1 Clinical	Amcure Gmbh	Esophageal Squamous Cell Carcinoma; Solid tumours	Details
Clodronic acid/Hyaluronic acid		Phase 1 Clinical	Abiogen Pharma Spa	Osteoarthritis	Details
177Lu-AKIR001	177Lu-AKIR001	Phase 1 Clinical	Akiram Therapeutics AB	Carcinoma, Non-Small-Cell Lung; Head and Neck Neoplasms; Neoplasms; Thyroid Carcinoma, Anaplastic; Uterine Cervical Neoplasms; Vulvar Neoplasms	Details
BGC-0228	BGC-0228	Phase 1 Clinical	Brightgene Bio-Medical Technology Co Ltd	Solid tumours	Details