CD43

CD43 Molekülinformation

Englischer Name	Leukosialin	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	0	Target-Alias	GPL115，GALGP，Galactoglycoprotein，Leukocyte sialoglycoprotein，Sialophorin，CD43
Höchste Forschungs- und Entwicklungsphase	Preclinical

Englischer Name	Leukosialin
Target-Alias	GPL115，GALGP，Galactoglycoprotein，Leukocyte sialoglycoprotein，Sialophorin，CD43
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	0
Höchste Forschungs- und Entwicklungsphase	Preclinical

CD43 Produktliste

Attribut
Protein (1)Antibody (1)
Produktbibliothek
Online (2)
Spezies
Human (1)Mouse (1)
Etikett
His Tag (1)- (1)
Marker
Unconjugated (1)PE Labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
CD3-H52H9	Human	HEK293	Human CD43 / leukosialin Protein, His Tag (MALS & SPR verified)				In den Warenkorb legen
FABm065-01	Mouse	-	PE-Labeled Monoclonal Anti-Human CD43 Antibody, Mouse IgG1 (AS672) (0.03% Proclin)				In den Warenkorb legen

Gesamtmenge2

CD43 Molekülhintergrund

CD43, also designated Ly-48, leukosialin, sialophorin, leukocyte sialoglycoprotein and W3/13, is a large type I transmembrane glycoprotein enriched with O-glycosylation and sialylation sites. It binds to CD54 (ICAM-1), CD62E, CD169 (Siglec-1), CD328 (Siglec-7) and MHC Class I molecules. Widely expressed on T lymphocytes, thymocytes, monocytes, granulocytes, bone marrow stem cells, pre-B cells, activated B cells and plasma cells—but absent on resting peripheral blood B cells, red blood cells and nonhematopoietic cells—CD43 modulates leukocyte functions (bidirectional adhesion, T cell costimulation, apoptosis induction) via intercellular interactions. Enzymatic shedding of activated leukocyte surface CD43 may exert negative regulation on adaptive immune responses, making it a valuable target for flow cytometry analysis.