CCL24

CCL24 Molekülinformation

Englischer Name	Chemokine (C-C Motif) Ligand 24	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1	Target-Alias	Small Inducible Cytokine Subfamily A (Cys-Cys)， Member 24，Chemokine (C-C Motif) Ligand 24，Small-Inducible Cytokine A24，MPIF-2，Ckb-6，Chemokine CCL24，MPIF2，SCYA24，Eotaxin-2，CK-beta-6，Myeloid progenitor inhibitory factor 2，C-C motif chemokine 24，CCL24，C-C Motif Chemokine Ligand 24，Eosinophil Chemotactic Protein 2
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Englischer Name	Chemokine (C-C Motif) Ligand 24
Target-Alias	Small Inducible Cytokine Subfamily A (Cys-Cys)， Member 24，Chemokine (C-C Motif) Ligand 24，Small-Inducible Cytokine A24，MPIF-2，Ckb-6，Chemokine CCL24，MPIF2，SCYA24，Eotaxin-2，CK-beta-6，Myeloid progenitor inhibitory factor 2，C-C motif chemokine 24，CCL24，C-C Motif Chemokine Ligand 24，Eosinophil Chemotactic Protein 2
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

CCL24 Produktliste

Attribut
Protein (1)
Produktbibliothek
Online (1)
Spezies
Human (1)
Etikett
His Tag (1)
Marker
Unconjugated (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
CC4-H52H1	Human	HEK293	Human CCL24/Eotaxin-2 Protein, His Tag (HPLC verified)				In den Warenkorb legen

Gesamtmenge1

CCL24 Molekülhintergrund

C-C motif chemokine ligand 24 (CCL24), also known as eotaxin2, belongs to CC chemokines like MCP-1, and it mainly chemoattracts eosinophils. CCL24 can promote the separation of eosinophils from endothelial cells and then combine with its sole ligand to promote eosinophils to enter the tissue. CCL24 was not originally found in eosinophils but was first isolated from monocytes. Latest, it was found that the expression of CCL24 in the bronchial epithelial cells of asthma patients increased. CCL24 promotes immune cell trafficking and activation as well as profibrotic activities through the CCR3 receptor (C-C chemokine receptor type 3). Both CCL24 and CCR3 is involved in lung and skin inflammation and fibrosis.

CCL24 Molekülalias

C-C motif chemokine 24,CK-beta-6,Eosinophil chemotactic protein 2,Myeloid progenitor inhibitory factor 2,Small-inducible cytokine A24,Eotaxin-2,MPIF-2,SCYA24,MPIF2

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Nebokitug	CM-101	Phase 2 Clinical	Chemomab Therapeutics Ltd	Cholangitis, Sclerosing; Metabolic Dysfunction-Associated Steatotic Liver Disease; Scleroderma, Systemic	Details