CCL20

CCL20 Molekülinformation

Englischer Name	C-C motif chemokine 20	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	0	Target-Alias	Chemokine CCL20，Exodus-1，ST38，Chemokine (C-C Motif) Ligand 20，CCL20，LARC，C-C motif chemokine 20，SCYA20，MIP-3-alpha，C-C Motif Chemokine Ligand 20，Small Inducible Cytokine Subfamily A (Cys-Cys)， Member 20，Liver And Activation-Regulated Chemokine，Macrophage Inflammatory Protein 3 Alpha，MIP-3a，CKb4，Small-Inducible Cytokine A20，CC Chemokine LARC，MIP3A，Beta Chemokine Exodus-1，Beta-Chemokine Exodus-1，Exodus
Höchste Forschungs- und Entwicklungsphase	Preclinical

Englischer Name	C-C motif chemokine 20
Target-Alias	Chemokine CCL20，Exodus-1，ST38，Chemokine (C-C Motif) Ligand 20，CCL20，LARC，C-C motif chemokine 20，SCYA20，MIP-3-alpha，C-C Motif Chemokine Ligand 20，Small Inducible Cytokine Subfamily A (Cys-Cys)， Member 20，Liver And Activation-Regulated Chemokine，Macrophage Inflammatory Protein 3 Alpha，MIP-3a，CKb4，Small-Inducible Cytokine A20，CC Chemokine LARC，MIP3A，Beta Chemokine Exodus-1，Beta-Chemokine Exodus-1，Exodus
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	0
Höchste Forschungs- und Entwicklungsphase	Preclinical

CCL20 Produktliste

Attribut
Protein (1)
Produktbibliothek
Online (1)
Spezies
Human (1)
Etikett
His Tag (1)
Marker
Unconjugated (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
CC0-H51H3	Human	E. coli	Human CCL20 Protein, His Tag (HPLC verified)				In den Warenkorb legen

Gesamtmenge1

CCL20 Molekülhintergrund

C-C motif chemokine 20(CCL20) acts as a ligand for C-C chemokine receptor CCR6. Signals through binding and activation of CCR6 and induces a strong chemotactic response and mobilization of intracellular calcium ions. The ligand-receptor pair CCL20-CCR6 is responsible for the chemotaxis of dendritic cells (DC), effector/memory T-cells and B-cells and plays an important role at skin and mucosal surfaces under homeostatic and inflammatory conditions, as well as in pathology, including cancer and various autoimmune diseases. CCL20 acts as a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes . Involved in the recruitment of both the proinflammatory IL17 producing helper T-cells (Th17) and the regulatory T-cells (Treg) to sites of inflammation. Required for optimal migration of thymic natural regulatory T cells (nTregs) and DN1 early thymocyte progenitor cells (By similarity). C-terminal processed forms have been shown to be equally chemotactically active for leukocytes.

CCL20 Molekülalias

C-C motif chemokine 20,Beta-chemokine exodus-1,CC chemokine LARC,Liver and activation-regulated chemokine,Macrophage inflammatory protein 3 alpha,MIP-3-alpha,Small-inducible cytokine A20,CCL20