CCL2

CCL2 Molekülinformation

Englischer Name	C-C motif chemokine 2	Anzahl der inverkehr gebrachten Arzneimittel	1
Anzahl der klinischen Arzneimittel	3	Target-Alias	MCP1，HC11，Monocyte chemotactic protein 1，Monocyte chemoattractant protein 1，CCL2，C-C Motif Chemokine Ligand 2，Monocyte Chemotactic And Activating Factor，Monocyte Secretory Protein JE，Small Inducible Cytokine A2 (Monocyte Chemotactic Protein 1， Homologous To Mouse Sig-Je)，Small Inducible Cytokine Subfamily A (Cys-Cys)， Member 2，Monocyte Chemoattractant Protein-1，Chemokine (C-C Motif) Ligand 2，Small-Inducible Cytokine A2，SCYA2，MCP-1，MCAF，Monocyte Chemotactic Protein 1， Homologous To Mouse Sig-Je，C-C Motif Chemokine 2，HSMCR30，GDCF-2，SMC-CF，Chemokine CCL2，MGC9434
Höchste Forschungs- und Entwicklungsphase	Approved

Englischer Name	C-C motif chemokine 2
Target-Alias	MCP1，HC11，Monocyte chemotactic protein 1，Monocyte chemoattractant protein 1，CCL2，C-C Motif Chemokine Ligand 2，Monocyte Chemotactic And Activating Factor，Monocyte Secretory Protein JE，Small Inducible Cytokine A2 (Monocyte Chemotactic Protein 1， Homologous To Mouse Sig-Je)，Small Inducible Cytokine Subfamily A (Cys-Cys)， Member 2，Monocyte Chemoattractant Protein-1，Chemokine (C-C Motif) Ligand 2，Small-Inducible Cytokine A2，SCYA2，MCP-1，MCAF，Monocyte Chemotactic Protein 1， Homologous To Mouse Sig-Je，C-C Motif Chemokine 2，HSMCR30，GDCF-2，SMC-CF，Chemokine CCL2，MGC9434
Anzahl der inverkehr gebrachten Arzneimittel	1
Anzahl der klinischen Arzneimittel	3
Höchste Forschungs- und Entwicklungsphase	Approved

CCL2 Produktliste

Attribut
Protein (1)Kits (1)
Produktbibliothek
Online (2)
Spezies
Human (2)
Etikett
Fc Tag (1)- (1)
Marker
Unconjugated (1)- (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
CC2-H5255	Human	HEK293	Human CCL2 / MCP-1 Protein, Fc Tag (MALS verified)				In den Warenkorb legen
CEA-B036	Human	-	Human MCP-1 / CCL2 ELISA Kit				In den Warenkorb legen

Gesamtmenge2

CCL2 Molekülhintergrund

Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. CCL2, a member of the CC subfamily, is characterized by two adjacent cysteine residues. CCL2 displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

CCL2 Molekülalias

CCL2,C-C motif chemokine 2,MCP-1,MCAF

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
AFX-5931	AFX-5931	Phase 2 Clinical	Afecta Pharmaceuticals Inc	Eczema	Details
MW-151	MW01-9-034WH; MW-151; MW01-2-151SRM	Phase 1 Clinical	University Of Kentucky	Drug-Related Side Effects and Adverse Reactions; Poisoning	Details
64CU-DOTA-ECL1i		Phase 1 Clinical	Washington University School Of Medicine	Arteriosclerosis; Carotid Artery Diseases; Heart Diseases	Details