Cadherin-6

Cadherin-6 Molekülinformation

Englischer Name	Cadherin-6	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	5	Target-Alias	Kidney cadherin，K-cadherin，Cadherin 6， Type 2， K-Cadherin (Fetal Kidney)，K-Cadherin，Cadherin-6，Kidney Cadherin，CAD6，KCAD
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Englischer Name	Cadherin-6
Target-Alias	Kidney cadherin，K-cadherin，Cadherin 6， Type 2， K-Cadherin (Fetal Kidney)，K-Cadherin，Cadherin-6，Kidney Cadherin，CAD6，KCAD
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	5
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Cadherin-6 Produktliste

Attribut
Protein (9)Cell (1)Beads (1)
Produktbibliothek
Online (11)
Spezies
Human (7)Cynomolgus / Rhesus macaque (2)Mouse (1)Rat (1)
Etikett
His Tag (4)Fc Tag (4)His Tag & Avi Tag (1)- (2)
Marker
Unconjugated (8)Biotin-labeled (1)- (2)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT CA6-H5229	Human	HEK293	Human Cadherin-6 / KCAD / CDH6 Protein, His Tag, low endotoxin (HPLC verified)	In den Warenkorb legen
HOT CA6-H5258	Human	HEK293	Human Cadherin-6 / KCAD / CDH6 Protein, Fc Tag (MALS verified)	In den Warenkorb legen
HOT CA6-H82E3	Human	HEK293	Biotinylated Human Cadherin-6 / KCAD / CDH6 Protein, His,Avitag™ (MALS verified)	In den Warenkorb legen
HOT CA6-C52H3	Cynomolgus / Rhesus macaque	HEK293	Cynomolgus / Rhesus macaque Cadherin-6 / KCAD / CDH6 Protein, His Tag, low endotoxin	In den Warenkorb legen
CA6-H5253	Human	HEK293	Human Cadherin-6 / KCAD / CDH6 (19-486) Protein, Fc Tag (MALS verified)	In den Warenkorb legen
CA6-H5254	Human	HEK293	Human Cadherin-6 / KCAD / CDH6 (269-383) Protein, Fc Tag	In den Warenkorb legen
CHEK-ATP127	Human	HEK293	HEK293/Human Cadherin-6 Stable Cell Line	In den Warenkorb legen
MBC-K196	Human	-	Human Cadherin-6 coupled magnetic beads (2 µm)	In den Warenkorb legen
CA6-M52H8	Mouse	HEK293	Mouse Cadherin-6 / KCAD / CDH6 Protein, His Tag	In den Warenkorb legen
CA6-C5253	Cynomolgus / Rhesus macaque	HEK293	Cynomolgus / Rhesus macaque Cadherin-6 / KCAD / CDH6 Protein, Fc Tag (MALS verified)	In den Warenkorb legen

Gesamtmenge11

Cadherin-6 Molekülhintergrund

Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH6 / KCAD contains five cadherin domains. CDH6 is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.

Cadherin-6 Molekülalias

CDH6,CAD6,KCAD,K-cadherin,Cadherin-6

Antikörperprojekt-Handelsplattform

Projektname	Projektphase	Molekültyp	Molekülquelle	Krankheitsgebiet	Indikationen
CDH6 mAb - 01	PCC	Monoclonal	Humanized Mouse	Solid Tumor	Ovarian cancer,Renal cell carcinoma

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Raludotatug deruxtecan	DS-6000a; DS6000a; DS-6000; R-DXd; MK-5909	Phase 3 Clinical	Daiichi Sankyo Co Ltd	Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Fallopian Tube Neoplasms; Gastrointestinal Neoplasms; Lung Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Solid tumours	Details
QLS-5133	QLS-5133; QLS5133	Phase 2 Clinical	Qilu Pharmaceutical Co Ltd	Solid tumours	Details
HS-20124	HS-20124; HS20124	Phase 1 Clinical	Hansoh BioMedical R&D Company	Solid tumours	Details
SIM-0505	SIM-0505	Phase 1 Clinical	Hainan Xiansheng Re Ming Pharmaceutical Co Ltd	Solid tumours	Details
AMT-707	AMT-707; CUSP-06	Phase 1 Clinical	Multitude Therapeutics Inc	Carcinoma, Renal Cell; Cholangiocarcinoma; Ovarian Neoplasms; Solid tumours	Details

Produktrezensionen

1***62022-08-09
1Menschen mögen
Human Cadherin-6 / KCAD / CDH6 Protein, His Tag, low endotoxin (HPLC verified)
Validated by SPR, measured monovalent affinity, anti-human FC chip, load diluted antibody, added diluted CDH6, His tag, with the affinity constant of 4.72 nM.