CA125

CA125 Molekülinformation

Englischer Name	Mucin-16	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	11	Target-Alias	Mucin-16 Short Isoform，Mucin-16 Long Isoform，Ovarian carcinoma antigen CA125，Ovarian cancer-related tumor marker CA125，MUC16，MUC-16，CA-125，Mucin 16， Cell Surface Associated，CA125，CA125 Ovarian Cancer Antigen，Mucin-16，CA-125 Antigen，FLJ14303
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Englischer Name	Mucin-16
Target-Alias	Mucin-16 Short Isoform，Mucin-16 Long Isoform，Ovarian carcinoma antigen CA125，Ovarian cancer-related tumor marker CA125，MUC16，MUC-16，CA-125，Mucin 16， Cell Surface Associated，CA125，CA125 Ovarian Cancer Antigen，Mucin-16，CA-125 Antigen，FLJ14303
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	11
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

CA125 Produktliste

Attribut
Protein (8)
Produktbibliothek
Online (8)
Spezies
Human (3)Cynomolgus (2)Mouse (1)Rabbit (1)Rat (1)
Etikett
Fc Tag & Avi Tag (2)His Tag (5)His Tag & Avi Tag (1)
Marker
Biotin-labeled (3)Unconjugated (5)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT CA5-H52H6	Human	HEK293	Human CA125 / MUC16 (13810-14451) Protein, His Tag, low endotoxin (MALS verified)	In den Warenkorb legen
HOT CA5-H82F4	Human	HEK293	Biotinylated Human CA125 / MUC16 Protein, Fc,Avitag™	In den Warenkorb legen
HOT CA5-H82F8	Human	HEK293	Biotinylated Human CA125 / MUC16 (13810-14451) Protein, Fc,Avitag™	In den Warenkorb legen
CA5-M52H6	Mouse	HEK293	Mouse CA125 / MUC16 Protein, His Tag (MALS verified)	In den Warenkorb legen
CA5-C52H8	Cynomolgus	HEK293	Cynomolgus CA125 / MUC16 Protein, His Tag, low endotoxin (MALS verified)	In den Warenkorb legen
CA5-C82E9	Cynomolgus	HEK293	Biotinylated Cynomolgus CA125 / MUC16 Protein, His,Avitag™ (MALS verified)	In den Warenkorb legen
CA5-R52H4	Rabbit	HEK293	Rabbit CA125 / MUC16 Protein, His Tag	In den Warenkorb legen
CA5-R52H5	Rat	HEK293	Rat CA125 Protein, His Tag (MALS verified)	In den Warenkorb legen

Gesamtmenge8

CA125 Molekülhintergrund

The CA125, also known as the MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. The CA 125 molecule is almost certainly a glycoprotein with a predominance of O-linkages. It is heterogeneous with regard to both size and charge, most likely due to continuous deglycosylation of side chains during its life-span in bodily fluids. It exists as a very large complex (perhaps as much as 4 million daltons) under natural conditions.

CA125 Molekülalias

CA125,CA-125,CA125MUC-16,FLJ14303,MUC16,mucin 16,mucin-16

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Oregovomab	B43.13	Phase 3 Clinical	Paladin Pharma	Abdominal Neoplasms; Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms	Details
EB-NK-FM (FRalpha/MUC16)	EB-NK-FM	Phase 2 Clinical	Beijing Biotech	Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Peritoneal Neoplasms	Details
EB-NK-MM (MSLN/MUC16)	EB-NK-MM	Phase 2 Clinical	Beijing Biotech	Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Peritoneal Neoplasms	Details
LBL-033	LBL-033	Phase 2 Clinical	Nanjing Leadsbiolabs Co Ltd	Neoplasms	Details
REGN-5668	REGN-5668	Phase 2 Clinical	Regeneron Pharmaceuticals Inc	Endometrial Neoplasms; Fallopian Tube Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms	Details
Ubamatamab	REGN-4018	Phase 2 Clinical	Regeneron Pharmaceuticals Inc	Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Fallopian Tube Neoplasms; Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms	Details
PRGN-3005	PRGN-3005	Phase 1 Clinical	Precigen Inc	Esophageal Neoplasms; Fallopian Tube Neoplasms; Lymphoma, Non-Hodgkin; Ovarian Neoplasms; Peritoneal Neoplasms; Sarcoma; Uterine Cervical Neoplasms	Details
GB-5267	GB-5267	Phase 1 Clinical	Generate Biomedicines Inc	Ovarian Neoplasms	Details
HWK-016	HWK-016	Phase 1 Clinical	Wuxi Biologics Co Ltd	Endometrial Neoplasms; Ovarian Neoplasms; Uterine Cervical Neoplasms	Details
JCAR-020	JCAR-020	Phase 1 Clinical	Eureka Therapeutics Inc, Juno Therapeutics Inc, Memorial Sloan Kettering Cancer Center	Solid tumours	Details
Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy(Regeneron Pharmaceutical)	27T-51; 27T51	Phase 1 Clinical	Regeneron Pharmaceuticals Inc	Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Peritoneal Neoplasms	Details

Produktrezensionen

E***e2025-08-07
0Menschen mögen
Human CA125 / MUC16 (13810-14451) Protein, His Tag, low endotoxin (MALS verified)
We used Acro Biosystems' recombinant Human CA125 / MUC16 protein (Catalog #CA5-H52H6) as a target antigen for antibody screening and downstream validation. The protein was employed in both ELISA and FACS assays. In ELISA, we observed strong, dose-dependent binding with minimal background, which enabled clear differentiation of candidate clones. For FACS, we used the protein to confirm surface staining specificity on engineered cell lines, and the results were consistent and reproducible. I was particularly impressed with the proteins high purity.