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BTN2A1

BTN2A1 Produktliste

  • Attribut

    Protein (3)

  • Produktbibliothek

    Online (3)

  • Spezies

    Human (3)

  • Etikett

    Fc Tag & Avi Tag (1)His Tag (1)His Tag & Avi Tag (1)

  • Marker

    Biotin-labeled (2)Unconjugated (1)

BTN2A1 Molekülhintergrund

Duplication events have led to three paralogues of BTN2A in primates: BTN2A1, BTN2A2, and BTN2A3. In humans, only BTN2A1 has been functionally characterised; it has been detected on epithelial cells and leukocytes, and identified as a novel ligand of dendritic cell-specific ICAM-3 grabbing nonintegrin (DCSIGN), a C-type lectin receptor that acts as an internalization receptor for HIV-1, HCV, and other pathogens. BTN2A2 mRNA has been shown to be expressed in circulating human immune cells.
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