ASGR1 Molekülinformation
Molecule Name
Asialoglycoprotein receptor 1
Molekülalias
ASGP-R 1, ASGPR 1, C-type lectin domain family 4 member H1, Hepatic lectin H1, HL-1
Drug Development Progress
Anzahl der klinischen Arzneimittel1
Anzahl der inverkehr gebrachten Arzneimittel0
Höchste Forschungs- und EntwicklungsphasePhase 2 Clinical
Target-Alias
HL-1，C-type lectin domain family 4 member H1，Hepatic lectin H1，ASGPR 1，ASGR1，Asialoglycoprotein Receptor 1，CLEC4H1，ASGP-R 1，ASGPR1
Molekülhintergrund
ASGPR, a transmembrane C-type lectin, recognizes a wide variety of ligands that contain either terminal galactose (Gal) or N-acetylgalactosamine (GalNAc) residues and has been identified as a highly selective receptor on hepatocytes. The ASGR is composed of both a major (ASGR1) and minor subunit (ASGR2). ASGR1 has been shown to be efficiently targeted to the plasma membrane and to undergo constitutive endocytosis and recycling and found mainly expressed in the human liver.
ASGR1 Produktliste
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N***i2024-11-25I recently purchased the hASGPR protein from Acro Biosystems for use in my SPR (surface plasmon resonance) experiments, and I am thrilled with the results! The protein quality was excellent, and it delivered reliable and reproducible data, which significantly boosted the confidence in my study. The purity and functional activity of the hASGPR were clearly top-notch, making it easy to work with and yielding strong, clean sensorgrams. I am particularly impressed with how well it performed in terms of binding affinity and kinetics analysis, which was a critical aspect of my research. Shipping was also quick, and the product was well-packaged to maintain its integrity. Overall, I highly recommend this product to anyone conducting SPR experiments requiring hASGPR. Great product and great experience!