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ASGR1

ASGR1 Molekülinformation

Englischer NameAsialoglycoprotein receptor 1Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel1Target-AliasHL-1,C-type lectin domain family 4 member H1,Hepatic lectin H1,ASGPR 1,ASGR1,Asialoglycoprotein Receptor 1,CLEC4H1,ASGP-R 1,ASGPR1
Höchste Forschungs- und EntwicklungsphasePhase 2 Clinical
Englischer NameAsialoglycoprotein receptor 1
Target-AliasHL-1,C-type lectin domain family 4 member H1,Hepatic lectin H1,ASGPR 1,ASGR1,Asialoglycoprotein Receptor 1,CLEC4H1,ASGP-R 1,ASGPR1
Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel1
Höchste Forschungs- und EntwicklungsphasePhase 2 Clinical

ASGR1 Molekülhintergrund

This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

ASGR1 Molekülalias

ASGP-R 1, ASGPR 1, C-type lectin domain family 4 member H1, Hepatic lectin H1, HL-1

Klinische Arzneimittelinformation

Englischer NameForschungscodeForschungsphaseFirmaIndikationenKlinische Studie
Kylo-11Kylo-11; Kylo11Phase 2 ClinicalShanghai Hejiya Biopharmaceutical Co Ltd, Xiamen Ganbaoli Biopharmaceutical Co LtdAtherosclerosis; Cardiovascular Diseases; Hyperlipoproteinemias; Lipid Metabolism Disorders
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Produktrezensionen

  • N***i2024-11-25
    1Menschen mögen
    I recently purchased the hASGPR protein from Acro Biosystems for use in my SPR (surface plasmon resonance) experiments, and I am thrilled with the results! The protein quality was excellent, and it delivered reliable and reproducible data, which significantly boosted the confidence in my study. The purity and functional activity of the hASGPR were clearly top-notch, making it easy to work with and yielding strong, clean sensorgrams. I am particularly impressed with how well it performed in terms of binding affinity and kinetics analysis, which was a critical aspect of my research. Shipping was also quick, and the product was well-packaged to maintain its integrity. Overall, I highly recommend this product to anyone conducting SPR experiments requiring hASGPR. Great product and great experience!
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