Angiogenin

Angiogenin Molekülinformation

Englischer Name	Angiogenin	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	0	Target-Alias	Ribonuclease 5，RNASE5，RAA1，Homo Sapiens Epididymis Luminal Protein 168，Angiogenin， Ribonuclease， RNase A Family， 5，Ribonuclease A Family Member 5，RNase 5，HEL168，Epididymis Luminal Protein 168
Höchste Forschungs- und Entwicklungsphase	Preclinical

Englischer Name	Angiogenin
Target-Alias	Ribonuclease 5，RNASE5，RAA1，Homo Sapiens Epididymis Luminal Protein 168，Angiogenin， Ribonuclease， RNase A Family， 5，Ribonuclease A Family Member 5，RNase 5，HEL168，Epididymis Luminal Protein 168
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	0
Höchste Forschungs- und Entwicklungsphase	Preclinical

Angiogenin Produktliste

Attribut
Protein (1)
Produktbibliothek
Online (1)
Spezies
Human (1)
Etikett
His Tag (1)
Marker
Unconjugated (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
ANN-H5149	Human	E. coli	Human Angiogenin / RNASE5 Protein, His Tag (SPR verified)				In den Warenkorb legen

Gesamtmenge1

Angiogenin Molekülhintergrund

Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo