Amphiregulin

Amphiregulin Molekülinformation

Englischer Name	Amphiregulin	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	2	Target-Alias	AREGB，Colorectum cell-derived growth factor，AR，Schwannoma-Derived Growth Factor，Amphiregulin B，CRDGF，SDGF，SDGF GN
Höchste Forschungs- und Entwicklungsphase	Phase 1 Clinical

Englischer Name	Amphiregulin
Target-Alias	AREGB，Colorectum cell-derived growth factor，AR，Schwannoma-Derived Growth Factor，Amphiregulin B，CRDGF，SDGF，SDGF GN
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	2
Höchste Forschungs- und Entwicklungsphase	Phase 1 Clinical

Amphiregulin Produktliste

Attribut
Protein (2)
Produktbibliothek
Online (2)
Spezies
Human (2)
Etikett
His Tag & Avi Tag (2)
Marker
Biotin-labeled (2)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
AMN-H82Q3	Human	HEK293	Biotinylated Human Amphiregulin Protein, His,Avitag™				In den Warenkorb legen
AMN-H82Q4	Human	HEK293	Biotinylated Human Amphiregulin Protein, His,Avitag™ (HPLC verified)				In den Warenkorb legen

Gesamtmenge2

Produktanfrage

Amphiregulin Molekülhintergrund

Amphiregulin (AREG), which acts as one of the ligands for epidermal receptor growth factor receptor (EGFR), plays a crucial role in tissue repair, inflammation, and immunity. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014]

Amphiregulin Molekülalias

AR, AREGB, CRDGF, SDGF

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
SRN-001	SRN-001	Phase 1 Clinical	siRNAgen Therapeutics Inc	Metabolic Dysfunction-Associated Steatotic Liver Disease; Idiopathic Pulmonary Fibrosis; Chronic Kidney Disease-Mineral and Bone Disorder	Details
PMG-1015	PMG-1015	Phase 1 Clinical	Pulmongene Ltd	Idiopathic Pulmonary Fibrosis	Details