Human SLC1A5 Full Length Protein, His,Flag Tag (Nanodisc-pro)

Cat. No. / Size
Price
Availability
Qty
SL5-H52D3-20ug
$750.00
In Stock - Delivery in 1-2 business days
SL5-H52D3-100ug
$1,500.00
In Stock - Delivery in 2-3 weeks
SL5-H52D3-500ug
$4,800.00
SL5-H52D3
Sub-Total :
$ 0
Customize Product Request Quote
Contact Us
Contact Us
Sub-Total:
$ 0
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Application
  • Cell based assay (FACS or functional assay)
  • Affinity testing (SPR / BLI)
  • Screening (ELISA)
Synonyms

ASCT2, M7V1, RDR, RDRC, ATB(0), AAAT, ASCT2M7VS1, M7V1ATBO, R16, RD114, RDRCFLJ31068

Source

Nanodisc-pro Human SLC1A5 Full Length Protein, His,Flag Tag (SL5-H52D3) is expressed from human 293 cells (HEK293). It contains AA Val 2 - Met 541 (Accession # Q15758-1).

Molecular Characterization

This protein carries a polyhistidine tag at the N-terminus and a Flag tag at the C-terminus.

*The isotype control of empty/mock nanodisc (Cat. No. APO-H5143) is sold separately and not included in protein, you can follow the link for product information.

Structure

Nanodisc-pro membrane protein is wrapped by a piece of cell membrane and scaffold, the info of scaffold can be found in above red text "isotope type control...".

Synthesis Process

Nanodisc-pro membrane protein extraction is a gentle, non-disruptive process that directly isolates full-length transmembrane proteins together with their surrounding native phospholipids from cellular membranes, without breaking or disturbing the original membrane structure. This preserves the membrane protein's natural conformational landscape and native lipid environment, yielding stable nanodisc that retain cellular phospholipids, with fully preserved biological activity—making them ideal for cell-based assays such as FACS and binding assays in antibody discovery and screening (ELISA), etc.

Purity

>90% as determined by SDS-PAGE.

Formulation

Supplied as 0.2 μm filtered solution in 20 mM HEPES, 150 mM NaCl, pH7.5 with glycerol as protectant.

Contact us for customized product form or formulation.

Shipping and Storage

This product is supplied and shipped on dry ice.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 12 months under sterile conditions.

Background

SLC1A5, a neutral amino acid transporter mediating glutamine uptake essential for rapidly proliferating cancer cells. It fuels the TCA cycle, nucleotide biosynthesis, and mTORC1 signaling. SLC1A5 is a metabolic oncology target; inhibitors aim to starve tumors of glutamine and induce metabolic crisis and growth arrest.