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Human SLC1A5 Protein, His Tag, TrxA Tag

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Product Number/Spec
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SL5-H5149-100ug
$360.00
In Stock - Delivery in 2-3 business days
SL5-H5149-1mg (100ug X 10)
$2615.00
In Stock - Delivery in 2 weeks
Gesamtanzahl Product Amount$ 0

Product Details

  • Synonyms

    ASCT2, M7V1, RDR, RDRC, ATB(0), AAAT, ASCT2M7VS1, M7V1ATBO, R16, RD114, RDRCFLJ31068

  • Source

    Human SLC1A5, His Tag, TrxA Tag (SL5-H5149) is expressed from E. coli cells. It contains AA Gln 154 - Gln 224 (Accession # Q15758-1).

    Predicted N-terminus: Met

    Request for sequence
  • Molecular Characterization

    SLC1A5 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the N-terminus, followed by a TrxA tag. The protein has a calculated MW of 22.5 kDa. The protein migrates as 24 kDa under reducing (R) condition (SDS-PAGE).

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Data Display

  • SDS-PAGE

    SLC1A5 SDS-PAGE

    Human SLC1A5, His Tag, TrxA Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

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FAQ

  • product

    Can lyophilized proteins remain stable during room-temperature shipping or temporary room-temperature exposure?

    In general, lyophilized proteins remain stable during room-temperature shipping or temporary exposure to room-temperature conditions.


    Many ACROBiosystems recombinant proteins are supplied in lyophilized (freeze-dried) form. The lyophilization process effectively removes moisture from the product, helping reduce degradation-related reactions and improve protein stability during transportation and storage.


    To evaluate the stability of lyophilized proteins under normal temperature conditions, ACROBiosystems conducted a stability study on 11 representative lyophilized protein products at 37°C. The study demonstrated that these proteins maintained good quality stability after storage at 37°C for approximately 20 days. Based on these validation results, temporary room-temperature exposure during shipping or handling is generally not expected to have a significant impact on product quality or downstream application performance.


    To ensure optimal long-term stability, products should be stored according to the storage conditions specified in the product Certificate of Analysis (COA) upon receipt.


    Supporting Document


Background Introduction

Sodium-dependent amino acids transporter(SLC1A5) that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904).

Frontier Progress

 
Drug Development Progress
  • English Name:

    Neutral amino acid transporter B(0)

  • Category:

  • Listed Drugs Count:

    0 Details

  • Clinical Drugs Count:

    0 Details

  • Highest R&D Stage:

    Preclinical

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