Mein Warenkorb

PE-Labeled Human LAG-3 / CD223 Protein, His TagStar Staining

User Reviews
Product Number/Spec
Price
Menge
LA3-HP2H4-25tests
$360.00
LA3-HP2H4-200tests
$2245.00
ETA of in-stock products:2 business days
Gesamtanzahl Product Amount$ 0

Product Details

  • Synonyms

    LAG3, CD223, FDC

  • Source

    PE-Labeled Human LAG-3 Protein, His Tag (LA3-HP2H4) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Leu 450 (Accession # P18627-1).

    Predicted N-terminus: Leu 23

  • Molecular Characterization

    This protein carries a polyhistidine tag at the C-terminus.

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, 0.2% BSA, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

Kunden haben auch angesehen

Data Display

  • Bioactivity-FACS

     LAG-3 FACS

    Flow cytometric analysis of Daudi cells staining with PE-Labeled Human LAG-3 / CD223 Protein, His TagStar Staining (Cat. No. LA3-HP2H4) at 1:10 dilution (10 μL of the antibody stock solution corresponds to labeling of 5e5 cells in a final volume of 100 µL), compared with negative control protein. PE signal was used to evaluate the binding activity (QC tested).

    Protocol

User Reviews
Publish Comment

Background Introduction

Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.

Frontier Progress

 
Drug Development Progress
  • English Name:

    Lymphocyte activation gene 3 protein

  • Category:

  • Listed Drugs Count:

    1 Details

  • Clinical Drugs Count:

    32 Details

  • Highest R&D Stage:

    Approved

Drug Candidate Licensing
More
  • Basic Product Information
  • Product Details
  • Kunden haben auch angesehen
  • Data Display
  • User Reviews
  • Hintergrund
Kontaktieren Sie uns