IdeS (70U/μl)

This product is derived from Streptococcus pyogenes and expressed in E. coli, it is an IgG-specific cysteine protease that digests antibodies at a single amino acid site below the hinge, generating homogenous F(ab’)2 and Fc fragments.

IdeS cleaves IgG to produce F(ab')2 and Fc fragments at specific site.

One unit digests ≥ 95% of 1 μg human IgG when incubated in 10 mM sodium phosphate, 137 mM NaCl, 2.7 mM KCl, pH7.4 at 37°C for 30min.

>95% as determined by SDS-PAGE.

>70 U/μL

Less than 1.0 EU per μg by the LAL method / rFC method.

Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with trehalose as protectant.

Contact us for customized product form or formulation.

This product is shipped at ambient temperature.

• -20°C to -70°C for 12 months in lyophilized state;
• -70°C for 12 months under sterile conditions after reconstitution.