Human Iba1 / AIF-1 Protein, His Tag

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Cat. No. / Size
Price
Qty
IB1-H51H9-100ug
$270.00
IB1-H51H9-1mg
$1700.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    Iba1, AIF-1, AIF1, G1, IBA1, LCP1

  • Source

    Human Iba1, His Tag (IB1-H51H9) is expressed from E. coli cells. It contains AA Met 1 - Pro 147 (Accession # P55008-1).

    Predicted N-terminus: Met 1

    Request for sequence
  • Molecular Characterization

    Iba1 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 18.6 kDa. The protein migrates as 18-20 kDa under reducing (R) condition (SDS-PAGE).

  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    Iba1 SDS-PAGE

    Human Iba1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

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Background

Allograft inflammatory factor 1 (AIF1), also known as IBA1, daintain and Protein G1, is an actin-binding protein. Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

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