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Human BST1 Protein, His Tag (MALS verified)

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Menge
BS1-H52H9-100ug
$410.00
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BS1-H52H9-1mg
$2,720.00
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BS1-H52H9
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Synonyms

ADP-ribosyl cyclase 2, CD157

Source

Human BST1, His Tag (BS1-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gly 29 - Ala 293 (Accession # Q10588-1).

Predicted N-terminus: Gly 29

Molecular Characterization
Other Tags and Version Biotin & Other Labeled Version

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 32.1 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

The protein is designed as a dimer.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>95% as determined by SDS-PAGE.

>95% as determined by SEC-MALS.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System

Background Introduction

Bone marrow stromal cell antigen-1(BST-1) or CD157 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that belongs to the CD38 family. CD157 was discovered in a bone marrow stromal cell line where it facilitates pre-B-cell growth.BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.