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Human BST1 Protein, His Tag (MALS verified)

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Product Number/Spec
Price
Menge
BS1-H52H9-100ug
$410.00
BS1-H52H9-1mg
$2720.00
ETA of in-stock products:2 business days
Gesamtanzahl Product Amount$ 0

Product Details

  • Synonyms

    ADP-ribosyl cyclase 2, CD157

  • Source

    Human BST1, His Tag (BS1-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gly 29 - Ala 293 (Accession # Q10588-1).

    Predicted N-terminus: Gly 29

    Request for sequence
  • Molecular Characterization

    BST1 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 32.1 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    The protein is designed as a dimer.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Data Display

  • SDS-PAGE

    BST1 SDS-PAGE

    Human BST1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • SEC-MALS

    BST1 SEC-MALS

    The purity of Human BST1, His Tag (Cat. No. BS1-H52H9) is more than 95% and the molecular weight of this protein is around 80-95 kDa verified by SEC-MALS.

    Report

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Publish Comment

Background Introduction

Bone marrow stromal cell antigen-1(BST-1) or CD157 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that belongs to the CD38 family. CD157 was discovered in a bone marrow stromal cell line where it facilitates pre-B-cell growth.BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.

Frontier Progress

 
Drug Development Progress
  • English Name:

    ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2

  • Category:

  • Listed Drugs Count:

    0 Details

  • Clinical Drugs Count:

    0 Details

  • Highest R&D Stage:

    Discontinued

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