Mogengel Matrix Organoid Culture (Acro Certified)

Mogengel Matrix Organoid Culture is intended to be used for robust, reproducible organoid culturing. For organoids that are harder to culture with other types of culturing media, try this series of Mogengel Matrix to ensure effectiveness and reproducibility of organoid studies. This includes studies on mouse intestinal organoids, lung organoids, human brain organoids, and so on.

• Basement membranes are comprised of continuous sheets of a specialized extracellular matrix. It acts an interface between various types of cells, including muscle, neuronal, epithelial, or endothelial cells, along with adjacent stroma. Basement membranes are an essential part in the organization of tissues forming the scaffolding and support for cellular growth and cell layers. They also affect a variety of cellular mechanisms such as adhesion, migration, proliferation, and differentiation. Basement membranes are selectively degraded and regenerated during development and wound healing, forming the base scaffold for tissue reconstruction. Basement membranes also act as a major barrier to invasion by metastatic tumor cells.
• Mogengel Matrix Organoid Culture is a soluble form of basement membrane that is purified from gene-edited mouse tumor cells grown in LDEV-free mouse populations. Reconstitution into the original basement membrane form occurs at 37℃ and is mainly comprised of laminin, collagen IV, entactin, and heparin sulfate proteoglycan.