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Product Details
- ProductSizeAmountActiveMax® Human VCAM-1 / CD106 μBeads, premium grade (for cells)2.5 mg2.5×10⁷ beadsActiveMax® Human VCAM-1 / CD106 μBeads, premium grade (for cells)10 mg (2.5 mg×4)1.0×10⁸ beads
Product Description
ActiveMax® Human VCAM-1 / CD106 μBeads, premium grade (for cells) are uniform, superparamagnetic beads of 5.5 µm in diameter immobilized with Human VCAM-1 / CD106 Protein, expressed from human 293 cells (HEK293) and contains AA Phe 25 - Glu 698(Accession # P19320-1).
ActiveMax® Human VCAM-1 / CD106 μBeads, premium grade (for cells) are produced under sterile manufacturing conditions (ISO 5) , and no animal- or human-derived components are used throughout the production process. It is produced under our rigorous quality control system that includes a comprehensive set of tests including sterility and endotoxin tests.Application
ActiveMax® Human VCAM-1 / CD106 μBeads, premium grade (for cells) is designed to synergistically activate Notch signaling in hematopoietic stem/progenitor cells (HSPCs). The synergistic interactions between Notch ligand Delta-like 4 and VCAM-1 are leveraged to enhance Notch signaling to support efficient T-cell lineage commitment, so the beads is recommended to use for in vitro production of induced pluripotent stem cell derived T cells coordinating with ActiveMax® Human DLL4 μBeads, premium grade (Cat. No. MBS-C013).
Reconstitution
See Certificate of Analysis (CoA) for detailed instruction.
Storage
This product is stable in storage under the following conditions: -20˚C for 12 months in lyophilized state. -70°C for 3 months under sterile conditions after reconstitution.
Please protect from light and avoid repeated freeze-thaw cycles. Immediate use after reconstitution is highly recommended.
Sterility
Negative
Endotoxin
Less than 0.002 EU per μg by the LAL method / rFC method.
Mycoplasma
Negative
Important Note
This product is for research use only and not intended for therapeutic or in vivo diagnostic use.
Formulation
Lyophilized in PBS with 0.1% HSA，pH 7.4. Trehalose is added as protectant before lyophilization.
ACRO Quality Management System
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Data Display
FACS Data
Assay of human VCAM-1 / CD106 protein on the μBeads surface by Flow cytometry. The human VCAM-1 / CD106 protein conjugated on the μBeads (Cat. No. MBS-C019) surface were fluorescently stained using PE anti-human CD106 Antibody, analyzed by flow cytometry (QC tested).
Protocol
User Reviews Publish Comment
Frontier Progress
Drug Development Progress- English Name：
Vascular cell adhesion molecule 1
- Category：
- Listed Drugs Count：
2 Details
- Clinical Drugs Count：
1 Details
- Highest R&D Stage：
Approved
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