Cellectra™ Human CD3 NanoDeplet Microbeads, Research grade

Cellectra™ Human CD3 NanoDeplet Microbeads, Research grade are dextran-coated superparamagnetic iron oxide nanoparticles of which the surface is conjugated with recombinant monoclonal antibodies specific to human CD3 (Isotype: mouse IgG1). They are especially designed for the depletion of CD3+ cells.
Cellectra™ Human CD3 NanoDeplet Microbeads, Research grade are produced under sterile manufacturing conditions (ISO 5), and no animal- or human-derived components are used throughout the production process. It is produced under our rigorous quality control system that includes a comprehensive set of tests including sterility and endotoxin tests.

Cellectra™ Human CD3 NanoDeplet Microbeads, Research grade are designed for the depletion of CD3⁺ cells from fresh or frozen human peripheral blood mononuclear cells (PBMCs). CD3E, also known as CD3 epsilon, is a member of the immunoglobulin superfamily found on mature T lymphocytes and most thymocytes. Depletion of T cells yields a purified non-T cell population suitable for diverse downstream applications. It supports the establishment of T cell-free systems to independently study innate immune cells such as NK cells, B cells, monocytes and dendritic cells for functional assays, single-cell sequencing and drug screening, eliminating experimental interference caused by T cells. The magnetic Microbeads are conjugated with monoclonal antibodies targeting human CD3 protein, enabling CD3+ cells to be labeled with the specific antibodies and magnetic particles, and separated using the separation columns and magnets.

For long term storage, the product should be stored in liquid state at -20°C or below Stability upon receipt: 1.Stable for 24 months at -20 °C or below; 2.Stable for 6 months at 2–8 °C under sterile conditions. Please protect from light and avoid repeated freeze-thaw cycles.

Negative

Less than 2 EU per mL by the LAL method / rFC method.

Negative

This product is for research use only and not intended for therapeutic or in vivo diagnostic use.

Supplied in PBS buffer containing EDTA, rHSA and Poloxamer 188.