Anti-Trastuzumab Antibody, Mouse IgG1 (6F2F7-2) (recommended for PK/PD)

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TRB-Y5b-100ug
$355.00
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TRB-Y5b-1mg (250ug X 4)
$2,695.00
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  • Product Details
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Source

Anti-Trastuzumab Antibody, Mouse IgG1 (6F2F7-2) is a recombinant mouse monoclonal antibody expressed in HEK293 cells.

Antibody Type

Recombinant Monoclonal

Clone

6F2F7-2

Isotype

Mouse IgG1, Kappa

Host Species

Mouse

Immunogen

Trastuzumab

Specificity

Recognizes Trastuzumab specifically.

Application
Application
Recommended Use
ELISA
0.2-2 μg/mL

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Purification

Protein A purified.

Aggregation

Less than 5%, as determined by SEC-MALS.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Lyophilized

Formulation

Lyophilized from a 0.22 μm-filtered solution in Tris (pH 7.5) containing 100 mM Glycine, 25 mM Arginine and 150 mM NaCl, with trehalose as protectant.

Please contact us for customized product forms or formulations.

Reconstitution

Please refer to the Certificate of Analysis (CoA) for specific instructions.

Shipping

Lyophilized product is shipped at ambient temperature.

Storage

For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 12 months under sterile conditions after reconstitution.
Notices

Product Specific Notices: For research use only.

Background

Trastuzumab, is a monoclonal antibody used to treat breast cancer. Specifically it is used for breast cancer that is HER2 receptor positive. Trastuzumab works by binding to the HER2 receptor and slowing down cell duplication. Trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein.