Recombinant Monoclonal Anti-PD-1 Antibody, Mouse (2F3)

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Menge
HGS-S238-20ul
$195.00
HGS-S238-100ul
$575.00
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Recombinant Monoclonal Anti-PD-1 Antibody, Mouse (2F3) is a PD-1 primary antibody for IHC application.

Antibody Type

Recombinant Monoclonal

Clone

2F3

Isotype

Mouse IgG

Host Species

Mouse

Reactivity

Human

Specificity

React with PD-1 protein on the membrane of target cell/tissue.

Application
Application
Recommended Use
IHC-P
1: 200 - 1: 1000

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Purification

Protein A purified.

Concentration

0.9~1.1 mg/ml

Form

Liquid

Formulation

Supplied a 0.22 μm-filtered solution in Tris buffer containing 1% BSA.

Please contact us for customized product forms or formulations.

Shipping

Liquid product is shipped at blue ice.

Storage

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • 2°C to 8°C for 14 days;
  • -20°C to -70°C for 12 months.
Notices

Product Specific Notices: For research use only.

Background Introduction

Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.

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